Overall bias methods and their use in sensitivity analysis of Cochrane reviews were not consistent.

Objective: The objective of the study was to analyze methods of assessing "overall bias" in Cochrane reviews of interventions published in the Cochrane Database of Systematic Reviews and sensitivity analyses related to overall risk of bias (RoB).

Study Design And Setting: From Cochrane reviews published within 3 years, from July 2015 to June 2018, we extracted data regarding methods of judging overall bias for a single trial, as well as details regarding methods used in frequency of RoB in sensitivity analyses.

Results: Of the 1,452 analyzed Cochrane reviews, 409 mentioned assessment of overall RoB on a study level.

Authors of trials from high-ranking anesthesiology journals were not willing to share raw data.

Objectives: To analyze data sharing practices among authors of randomized controlled trials (RCTs) published in seven high-ranking anesthesiology journals from 2014 to 2016.

Study Design And Setting: We analyzed data sharing statements in 619 included RCTs and contacted their corresponding authors, asking them to share de-identified raw data from trial.

Results: Of the 86 (14%) authors who responded to our query for data sharing, only 24 (4%) provided the requested data.