Publications by authors named "Jake Uy Sebastian"
Article Synopsis
- LASIK surgery can cause temporary dry eye due to nerve damage, but this study investigates long-term ocular surface changes, blinking rates, and meibomian gland health in post-LASIK patients at least 48 months post-surgery.
- The study involved 48 post-LASIK patients and 48 matched healthy controls, assessing clinical findings and imaging related to eye health.
- Findings showed that post-LASIK patients had lower meibum quality, reduced tear production, and high chronic dry eye symptom prevalence, indicating the need for thorough evaluations and treatments for affected patients.
This case report describes a novel surgical technique, the "levator switch," for correcting severe blepharoptosis in a 65-year-old man with poor Bell's phenomenon following previous bilateral ptosis surgery. He presented with recurrent ptosis, weak levator function, and excessive frontalis muscle use. The technique involves a sequential approach: anterior levator resection followed by repurposing the resected tissue as a posterior lamellar graft to the lower tarsal border.
View Article and Find Full Text PDFPurpose: This study aims to report correlations between thyroid-stimulating immunoglobulin (TSI) and both clinical and radiological parameters in recent-onset symptomatic thyroid eye disease (TED) patients.
Methods: A prospective cohort study of TED patients managed at the Chinese University of Hong Kong from January 2014 to May 2022. Serum TSI levels were determined with the functional assay.
Investigation of lacrimal gland and extraocular muscle in thyroid eye disease patients with severe subjective dry eye disease: a multiparametric magnetic resonance imaging study.
Graefes Arch Clin Exp Ophthalmol
August 2024
Purpose: To analyze the radiological features of the lacrimal gland (LG) and extraocular muscle (EOM) in thyroid eye disease (TED) patients with severe subjective dry eye disease (DED) using magnetic resonance imaging (MRI) measurements.
Methods: In this cross-sectional study, mechanical ocular exposure, dry eye assessment and MRI data were collected. Patients were classified into non-severe subjective DED group with ocular surface disease index (OSDI) < 33 and severe subjective DED group with OSDI ≥ 33.
Objectives: A subtype of patients with thyroid eye disease (TED) were found to be euthyroid without prior thyroid dysfunction or treatment, known as Euthyroid Graves' Ophthalmopathy (EGO). We report the prevalence, clinical and serological phenotypes of EGO in a Chinese population.
Methods: A cross-sectional follow-up study.
Purpose: Euthyroid Graves' ophthalmology (EGO) refers to the subgroup of thyroid eye disease patients with distinct clinical presentations. This study evaluated the ocular surface and meibomian gland changes in EGO patients.
Methods: A cross-sectional study was conducted at The Chinese University of Hong Kong including 34 EGO patients and 34 age-and sex- matched healthy controls.
Background: Immunoglobulin G4-related ophthalmic disease (IgG4-ROD) poses clinical challenges due to its heterogeneous ocular and systemic manifestations. We aim to report the systemic involvement and the clinical, serological and radiological associations of a cohort of Chinese patients.
Methods: A territory-wide, biopsy-proven, Chinese cohort.
Diagnosis of dysthyroid optic neuropathy (DON) typically relies on a set of diagnostic clinical features, including decreased visual acuity, impaired color vision, presence of relative afferent pupillary defect, optic disc swelling and ancillary tests including visual field (VF), pattern visual evoked potential (pVEP), and apical crowding or optic nerve stretching on neuroimaging. We summarize various diagnostic methods to establish or rule out DON. A total of 95 studies (involving 4619 DON eyes) met the inclusion criteria.
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