Publications by authors named "Jake Quarles"
Article Synopsis
- There is growing recognition that prostate cancer patients often have germline variants that can have significant implications for their health and that of their families, necessitating a deeper understanding of which individuals may carry these variants.
- A study involving 505 prostate cancer patients was conducted, tracking various factors and evaluating the presence of pathogenic or likely pathogenic (P/LP) germline variants through genetic testing aligned with NCCN guidelines.
- The study found that the occurrence of P/LP variants was similar across different age groups and clinical characteristics, with only the age at testing in metastatic patients showing a predictive association for these variants, indicating challenges in refining existing clinical guidelines.
Importance: As the field of medicine strives for equity in care, research showing the association of social determinants of health (SDOH) with poorer health care outcomes is needed to better inform quality improvement strategies.
Objective: To evaluate the association of SDOH with prostate cancer-specific mortality (PCSM) and overall survival (OS) among Black and White patients with prostate cancer.
Data Sources: A MEDLINE search was performed of prostate cancer comparative effectiveness research from January 1, 1960, to June 5, 2020.
Purpose: Indications for germline testing in prostate cancer patients have expanded substantially over the past decade. With a near-universal shortage of genetic counselors and increasing demand, increased access to genetic counseling is crucial. We sought to prospectively implement and assess a clinician-led approach to genetic counseling and testing.
View Article and Find Full Text PDFThe millennial generation has become the largest generation thus far and continues to grow, as it makes up a substantial part of the workforce. Often misunderstood, those identifying as millennials offer skills, traits, and characteristics that previous generations have been unable to provide. Learning to understand these millennials and all they have to offer serves key to a successful training program or practice.
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