Delayed radiation myelopathy: a case and treatment algorithm proposal.

Delayed radiation myelopathy is a rare but severe complication that causes progressive and irreversible patient deterioration. Although it is an exclusion diagnosis, there are factors associated with radiation doses and administration areas that may reduce the risk of its incidence. To date, there is no known first-line and effective treatment available to alleviate the symptoms.

Effectiveness of acute post-operative pain management by the acute pain service.

Background: Analgesia by specialists with formal training in pain management could be more effective, to find out, the results of a team of an acute pain service will be determined.

Methods: Retrospective study (n = 108) of post-operative (POP) analgesia; two evaluations were taken: before starting analgesics in the immediate POP period and the second at 24 h. A multivariate analysis was performed to establish independent risk factors associated with the effectiveness of the treatment.

Efficacy of opioids and non-opioid analgesics in the treatment of post procedure pain of burned patients: a narrative review.

Introduction: Burns are a common trauma that cause acute severe pain in up to 80% of patients. The objective of this narrative review is to evaluate the efficacy of opioids, non-steroidal anti-inflammatory drugs, paracetamol, gabapentinoids, ketamine, and lidocaine in the treatment of acute pain in burn victims.

Methodology: The databases explored were PubMed, Embase, ClinicalTrials, and OpenGrey.

Defining trajectories of acute pain in surgical patients short title: acute pain follow-up.

Introduction: Assessment of acute postoperative pain is mandatory for effective treatments. Pain trajectories may help professionals improve treatments. It has been suggested that uncontrolled pain in the immediate postoperative period generates higher pain intensities on the following days of hospital stay.

Opioids in the immune system: from experimental studies to clinical practice.

Opioids interact with both innate and adaptive immune systems and have direct effects on opioid receptors located on immune cells. Research on this topic has provided evidence of the opioid influence on the immune response associated with surgical stress. The immunological effects of opioids are currently being investigated, particularly whether they influence the outcome of surgery or the underlying disease regarding important aspects like infection or cancer progression.

Peri-articular injection of an analgesic mixture in primary total hip arthroplasty: an effective strategy for pain control during the first post-operative day.

Background: Previous studies of soft tissue infiltration in hip arthroplasty present variable results. The purpose of this study is to identify whether injection of an analgesic mixture improves pain management during the immediate post-operative period.

Materials And Methods: This cohort study compared 129 patients that received peri-articular soft tissue injection with 20 ml of 0.

Analgesic Effect of Dexamethasone after Arthroscopic Knee Surgery: A Randomized Controlled Trial.

Dexamethasone is sometimes used as a coanalgesic because of its anti-inflammatory properties. . To evaluate opioid use, postoperative pain intensity, and side effects after a single dose of dexamethasone in patients undergoing arthroscopic knee surgery.

A review of opioid prescription in a teaching hospital in Colombia.

Introduction: Review of opioid prescriptions in a hospital provides valuable information to health care professionals which may contribute to proper pain management; opioid utilization studies may help uncover factors that can be improved for better prescribing. To evaluate the use of opioid analgesics in a university hospital, a review of opioids prescribed in hospitalized patients was developed.

Methods: Information was obtained from the pharmacy database and medical records.

The influence of information leaflets on morphine consumption in postoperative patients using patient-controlled analgesia.

Negative preconceived beliefs about the benefits of morphine use are frequently seen in hospitalized patients and may be associated with reports of severe pain, poor patient satisfaction, impaired rehabilitation, and possibly more chronic postsurgical pain. In some patients, providing information through instructive leaflets may modify negative beliefs that limit proper medication use. The purpose of this study was to determine whether the morphine-related information provided through leaflets during the postoperative period led to increased use of morphine and lower pain scores in patients using patient-controlled analgesia.

The medical consumption of opioids in Colombia, 1997-2007.

The World Health Organization classifies opioid analgesics as essential medicines in the treatment of severe pain and recommends their increased availability. The combination of availability, training of professionals, and a legal framework granting access to these medicines has led to a sharp increase in the consumption of morphine and other opioids in developed countries. However, in Colombia, consumption of opioid analgesics appears to fail to meet patient needs.

Characteristics of the last hospital stay in terminal patients at an acute care hospital in Colombia.

Unlabelled: In Colombia, most palliative care is provided in acute care hospitals. In those settings, a palliative care approach could be limited because of a disease-oriented approach instead of patient-centered care.

Purpose: To know the framework of a typical Colombian university hospital that provides palliative care services.

Palliative sedation in Latin America: survey on practices and attitudes.

Introduction: Palliative sedation (PS) is the subject of ethical and legal debates worldwide. Statistics of its utilization are available in developed countries; however, in Latin America, these data are scarcely known. The purpose of this research was to determine the practices and attitudes of palliativists in Latin America towards PS.

Effects of parenteral hydration in terminally ill cancer patients: a preliminary study.

Purpose: Most patients with cancer develop decreased oral intake and dehydration before death. This study aimed to determine the effect of parenteral hydration on overall symptom control in terminally ill cancer patients with dehydration.

Patients And Methods: Patients with clinical evidence of mild to moderate dehydration and a liquid oral intake less than 1,000 mL/day were randomly assigned to receive either parenteral hydration with 1,000 mL (treatment group) or placebo with 100 mL normal saline administered over 4 hours for 2 days.

Corticotropin-releasing hormone (CRH) produces analgesia in a thermal injury model independent of its effect on systemic beta-endorphin and corticosterone.

To determine separately the effect of corticotropin-releasing hormone (CRH) on analgesia and on inflammation, rats were assigned to receive CRH 60 microg/kg, CRH 300 microg/kg, morphine 4 mg/kg, or normal saline intravenously 15 min before a burn injury. Two mesh chambers that allowed collection of fluid had been previously implanted subdermally in each rat. The skin overlying the right chamber was subject to thermal injury.

Methadone versus morphine as a first-line strong opioid for cancer pain: a randomized, double-blind study.

Purpose: To compare the effectiveness and side effects of methadone and morphine as first-line treatment with opioids for cancer pain.

Patients And Methods: Patients in international palliative care clinics with pain requiring initiation of strong opioids were randomly assigned to receive methadone (7.5 mg orally every 12 hours and 5 mg every 4 hours as needed) or morphine (15 mg sustained release every 12 hours and 5 mg every 4 hours as needed).