Histomorphometric analysis of the effects of creatine on rat myometrium.

Objective: To analyze the myometrial thickness of rats subjected to creatine (Cr) ingestion.

Study Design: A total of 14 rats was equally divided into the control group (ConGr) receiving 1 ml potable water and the creatine group (CrGr) subjected to the ingestion of 1.6 g/kg Cr diluted in 1 ml potable water.

Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle.

Objective: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle.

Design: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI - proestrous, GII - estrous, GIII - metaestrous and GIV - diestrous. Animals were sacrificed at each phase of the cycle, and the cervix was immediately removed and submitted to biochemical extraction and determination of sulfated glycosaminoglycans and hyaluronic acid.