Morphology Determines an Efficient Coherent Electron Transport for Push-Pull Organic Semiconductors Based on Triphenylamine and Dicyanovinyl Groups.

The morphology of the active layer in organic solar cells is fundamental for achieving high power conversion efficiency. However, the morphological characteristics for optimal performance are still being investigated. An atomistic computational approach is required to determine the relationship between active layer morphology and performance.

Platform for Healthcare Promotion and Cardiovascular Disease Prevention.

This article presents the hardware-software design and implementation of an open, integrated, and scalable healthcare platform oriented to multiple point-care scenarios for healthcare promotion and cardiovascular disease prevention. The platform has the capability to provide continuous monitoring, extended device integration, strategies based on artificial intelligence for the information analysis and cybersecurity support, delivering a secure end-to-end hardware-software solution. This platform is used to perform the remote patient health monitoring and supervision by doctors, triage procedures in hospitals, or self-care monitoring using personal devices such as tablets and cellphones.

Exomes of Ductal Luminal Breast Cancer Patients from Southwest Colombia: Gene Mutational Profile and Related Expression Alterations.

Cancer is one of the leading causes of mortality worldwide. Breast cancer is the most frequent cancer in women, and in recent years it has become a serious public health problem in Colombia. The development of large-scale omic techniques allows simultaneous analysis of all active genes in tumor cells versus normal cells, providing new ways to discover the drivers of malignant transformations.

Hardware Accelerator for the Multifractal Analysis of DNA Sequences.

The multifractal analysis has allowed to quantify the genetic variability and non-linear stability along the human genome sequence. It has some implications in explaining several genetic diseases given by some chromosome abnormalities, among other genetic particularities. The multifractal analysis of a genome is carried out by dividing the complete DNA sequence in smaller fragments and calculating the generalized dimension spectrum of each fragment using the chaos game representation and the box-counting method.

TRPV1 channel as a target for cancer therapy using CNT-based drug delivery systems.

Carbon nanotubes are being considered for the design of drug delivery systems (DDSs) due to their capacity to internalize molecules and control their release. However, for cellular uptake of drugs, this approach requires an active translocation pathway or a channel to transport the drug into the cell. To address this issue, it is suggested to use TRPV1 ion channels as a potential target for drug release by nano-DDSs since these channels are overexpressed in cancer cells and allow the permeation of large cationic molecules.