Introduction: In 1842 William Bowman described the microvascular system of the Malpighian body. Electron microscopic studies definitively revealed the spatial structure of its mesangial-capillary-epithelial component. In 1952-54 Trabucco and Marquez challenged the ideas of Bowman, demonstrating the existence of a single glomerular arteriole.
View Article and Find Full Text PDFA proposal of an updated system of the Organization of Scientific Biomedical Kowledge is presented, integrating the historical achievements in pathology from the 15 to the 21 century. Scientific understanding of disease (Human Biopathology) is actually acquired at consecutive levels: 1) Etiopathogenic, 2) Structural, 3) Physiopathological, and 4) Clinical. A complete spectrum of etiological factors is presented.
View Article and Find Full Text PDFBackground: Solid papillary carcinoma of the breast (SPCB) is a distinctive form of papillary carcinoma that tends to occur in older women and usually has a favorable prognosis.
Cases: We report the cytologic and histologic findings in four cases of SPCB. All but one of the patients were elderly women (mean age, 66 years).