Identification of Escherichia coli strains for the heterologous overexpression of soluble Clostridium difficile exosporium proteins.

Clostridium difficile infections are one of the leading causes of hospital-acquired infections. C. difficile spores are considered the morphotype of transmission and recurrent infection due to its natural spore resistance properties.

Protein composition of the outermost exosporium-like layer of Clostridium difficile 630 spores.

Unlabelled: Clostridium difficile spores are considered the morphotype of infection, transmission and persistence of C. difficile infections. There is a lack of information on the composition of the outermost exosporium layer of C.