Publications by authors named "Jaime Mazon-Ruiz"
Up to 50% of patients admitted for heart failure (HF) have congestion at discharge despite diagnostic and therapeutic advances. Both persistent congestion and diuretic resistance are associated with worse prognosis. The combination of hypertonic saline and loop diuretic has shown promising results in different studies.
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- * Current guidelines for treating AKI, like stopping diuretics and using albumin for fluid management, may not always be helpful and can sometimes worsen the patient's condition, leading to complications like fluid overload.
- * New techniques, such as hemodynamic point-of-care ultrasound (PoCUS), offer a better way to assess a patient’s fluid status and tailor treatments more effectively, without invasive procedures.
Hyponatremia is a multifactorial disorder defined as a decrease in plasma sodium concentration. Its differential diagnosis requires an adequate evaluation of the extracellular volume (ECV). However, ECV determination, simply based on the clinical history, vital signs, physical examination, and laboratory findings can leads to misdiagnosis and inappropriate treatment.
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- Kidney transplantation generally enhances patient survival, but early deaths after the procedure remain a concern.
- The study explores the role of growth differentiation factor 15 (GDF-15) as a potential mortality predictor in kidney transplant candidates, analyzing data from 395 recipients.
- Results show that higher GDF-15 levels are linked to increased mortality risk, even after adjusting for other clinical variables, and the inclusion of GDF-15 improves the accuracy of existing survival prediction models.
Immunosuppression withdrawal after graft failure seems to favor sensitization. A high percentage of calculated panel-reactive antibody (cPRA) and the development of de novo donor specific antibodies (dnDSA) indicate human leukocyte antigen (HLA) sensitization and may hinder the option of retransplantation. There are no established protocols on the immunosuppressive treatment that should be maintained after transplant failure.
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