Publications by authors named "Jaime Delgadillo-Velazquez"
The association between the size of adipocyte-derived extracellular vesicles and fasting serum triglyceride-glucose index as proxy measures of adipose tissue insulin resistance in a rat model of early-stage obesity.
Front Nutr
July 2024
Introduction: Obesity is a complex disease that predisposes individuals to cardiometabolic alterations. It leads to adipose tissue (AT) dysfunction, which triggers insulin resistance (IR). This suggests that people with obesity develop local IR first and systemic IR later.
View Article and Find Full Text PDFBackground: Gestational diabetes mellitus (GDM) represents the main metabolic alteration during pregnancy. The available methods for diagnosing GDM identify women when the disease is established, and pancreatic beta-cell insufficiency has occurred.The present study aimed to generate an early prediction model (under 18 weeks of gestation) to identify those women who will later be diagnosed with GDM.
View Article and Find Full Text PDFExtracellular vesicles (EVs) are nanoparticles secreted by cells under physiological and pathological conditions, such as metabolic diseases. In this context, EVs are considered potential key mediators in the physiopathology of obesity. It has been reported that EVs derived from adipose tissue (ADEVs) contribute to the development of a local inflammatory response that leads to adipose tissue dysfunction.
View Article and Find Full Text PDFArticle Synopsis
- Overweight and obesity in reproductive-age women can lead to insulin resistance and affect pregnancy metabolism, highlighting the need for metabolic adaptation during this time.
- In a study of 20 women with pre-gestational normal weight or overweight, metabolic flexibility was evaluated through blood tests and calorimetry across three trimesters.
- Results showed that while women with overweight had lower metabolic flexibility in the first trimester, they were more flexible in the second trimester, with no significant differences in the third semester, suggesting that metabolic flexibility varies throughout pregnancy and helps maintain balance between mother and fetus.*
Comparison of the prevalence of sarcopenia using skeletal muscle mass index and calf circumference applying the European consensus definition in elderly Mexican women.
Geriatr Gerontol Int
January 2017
Aim: To compare the prevalence of sarcopenia using two indicators: skeletal muscle mass index (SMI) and calf circumference (CC) used in the algorithm proposed by the European Working Group on Sarcopenia in Mexican elderly women.
Methods: This was a cross-sectional study. Lean body mass was determined by dual-energy X-ray absorptiometry.
A comparison of dual energy x-ray absorptiometry and two bioelectrical impedance analyzers to measure body fat percentage and fat-free mass index in a group of Mexican young women.
Nutr Hosp
May 2014
Introduction: Studies of obesity require the estimation of fat mass (FM) and fat-free mass (FFM); therefore it is important to validate methods that evaluate these measurements.
Objective: We sought to compare two different bioelectrical impedance analysis systems (BIAs) to estimate FM and FFM using dual-energy X-ray absorptiometry (DXA) as reference.
Methods: We used a cross-sectional design.
Background: Sarcopenia is a geriatric syndrome, which affects the functional status and mobility of individuals.
Objective: To identify the prevalence of sarcopenia and undernutrition, and to assess the association between sarcopenia and mobility, and sarcopenia and basic activities of daily living (ADL) in a group of elderly women.
Subjects And Methods: A cross-sectional study was performed in patients attending a geriatric service at a government hospital in Mexico City.