Botulinum Toxin A for Spastic Trismus Due to Brain Stem Encephalitis in a Pediatric Intensive Care Setting: A Unique Case Report.

Injection of botulinum toxin A to masseter and temporalis muscles improved mouth opening and facilitated suction and oral care in a child with spastic trismus. This is the first such report in a 3.5-year-old child on mechanical ventilator in pediatric intensive care unit setting.

Neuraminidase inhibitors for the treatment of influenza infection in people with cystic fibrosis.

Background: Cystic fibrosis is the most common, life-threatening, recessively inherited disease of Caucasian populations. It is a multisystem disorder caused by a mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator protein which is important in producing sweat, digestive juices and mucus.The impaired or absent function of this protein results in the production of viscous mucus within the lungs and an environment that is susceptible to chronic airway obstruction and pulmonary colonization by a range of pathogenic bacteria.