Publications by authors named "Jai Khurana"
Medical Reference Tools and Pharmaceutical Promotion: A History of Entanglement.
Ann Intern Med
December 2024
Reference tools are often uncritically accepted as balanced, objective, definitive, and evidence-based guides to medical knowledge. Yet for centuries textbooks and manuals have been entangled in various ways with industry interests. This essay shows how reference tools have served as sites of pharmaceutical promotion.
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- This study evaluates the link between pulmonary hypertension (PH) and mortality in infants and children with vein of Galen malformation (VOGM), analyzing data from 49 patients admitted to Boston Children's Hospital between 2007 and 2020.
- It was found that overall hospital survival rates were significantly higher for older children (age >60 days, 96%) compared to younger infants (age ≤60 days, 50%), with high output PH being a critical factor for those under 60 days.
- The resolution of PH is strongly tied to survival outcomes, while certain treatments like inhaled nitric oxide showed limited benefit in patients, emphasizing the need for effective management strategies in this patient group.*