Unconventional strategies for liver tissue engineering: plant, paper, silk and nanomaterial-based scaffolds.

The paper highlights how significant characteristics of liver can be modeled in tissue-engineered constructs using unconventional scaffolds. Hepatic lobular organization and metabolic zonation can be mimicked with decellularized plant structures with vasculature resembling a native-hepatic lobule vascular arrangement or silk blend scaffolds meticulously designed for guided cellular arrangement as hepatic patches or metabolic activities. The functionality of hepatocytes can be enhanced and maintained for long periods in naturally fibrous structures paving way for bioartificial liver development.

Unravelling the interaction between Influenza virus and the nuclear pore complex: insights into viral replication and host immune response.

Influenza viruses are known to cause severe respiratory infections in humans, often associated with significant morbidity and mortality rates. Virus replication relies on various host factors and pathways, which also determine the virus's infectious potential. Nonetheless, achieving a comprehensive understanding of how the virus interacts with host cellular components is essential for developing effective therapeutic strategies.

Mechanistic understanding on the uptake of micro-nano plastics by plants and its phytoremediation.

Contaminated soil is one of today's most difficult environmental issues, posing serious hazards to human health and the environment. Contaminants, particularly micro-nano plastics, have become more prevalent around the world, eventually ending up in the soil. Numerous studies have been conducted to investigate the interactions of micro-nano plastics in plants and agroecosystems.

Optimization of phytase production by in solid-state fermentation for potential as a feed additive.

The study aims to statistically optimize the phytase production by PBG30 in solid-state fermentation using wheat bran as substrate. Variables viz. pH, incubation days, MgSO, and Tween-80 were the significant parameters identified through the Plackett-Burman design (PBD) that majorly influenced the phytase production.

Significance of landfill microbial communities in biodegradation of polyethylene and nylon 6,6 microplastics.

Plastic pollution, particularly microplastics, poses a significant environmental challenge. This study aimed to address the urgent need for sustainable solutions to manage plastic waste. The degradation of polyethylene microplastics (PEMPs) and nylon 6,6 microplastics (NMPs) were investigated using bacterial culture isolates, isolated from a municipal landfill site and identified through 16 S rDNA as well as metagenomics techniques.

WITHDRAWN: Role of Oxidative Stress and Genetic Polymorphism of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in COPD.

Article in press withdrawn by publisher.

Biotherapeutic microbial supplementation for ameliorating fish health: developing trends in probiotics, prebiotics, and synbiotics use in finfish aquaculture.

Nutrition demands in aquaculture can be realized through quality aquafeeds as compounded diets that contribute to the growth and health of aquaculture species. Functional additives in feed, notably probiotics, prebiotics, and their admixture synbiotics, have been recently recognized for their biotherapeutic role as immunostimulants capable of conferring disease resistance, stress tolerance, and gastrointestinal health; counteracting the negative effects of anti-nutrients, pathogenic prevalence, and antimicrobials in finfish aquaculture. Formulated diets based on probiotics, prebiotics, and as a supplemental combination for synbiotics can significantly influence fish gut microbiomes, establishing the modalities of microbial dynamics to maximize host-associated benefits.

Effect of leaves and seeds of Achyranthes aspera as feed supplements on the immunological and stress parameters and related gene expressions of Asian catfish (Clarias batrachus).

The immunostimularory properties of Achyranthes aspera leaves and seeds supplemented feeds were evaluated in Asian catfish, Clarias batrachus (0.352±0.008 g).

Freshwater Macrophytes: A Potential Source of Minerals and Fatty Acids for Fish, Poultry, and Livestock.

The freshwater macrophytes are abundant in tropical and subtropical climates. These macrophytes may be used as feed ingredients for fish and other animals. The nutritional value of twelve freshwater-cultured macrophytes was evaluated in the present study.

Evaluation of UV-B protective properties of leaves and seeds of Achyranthes aspera in Asian catfish Clarias batrachus (Linn.).

The ultraviolet-B (UV-B) radiation is harmful to the aquatic organisms. The UV-B protective properties of leaves and seeds of herb Achyranthes aspera were evaluated in Clarias batrachus. Fish were fed with four diets-EFL1, EFL2 containing 0.

Insights into microbial diversity on plastisphere by multi-omics.

Plastic pollution is a major concern in marine environment as it takes many years to degrade and is one of the greatest threats to marine life. Plastic surface, referred to as plastisphere, provides habitat for growth and proliferation of various microorganisms. The discovery of these microbes is necessary to identify significant genes, enzymes and bioactive compounds that could help in bioremediation and other commercial applications.

Effect of Lemna minor supplemented diets on growth, digestive physiology and expression of fatty acids biosynthesis genes of Cyprinus carpio.

The potential nutritional value of duckweed Lemna minor (Lemnaceae) was evaluated for common carp Cyprinus carpio fry. Fish were fed diets containing five graded levels of duckweed: 0% (LM0, control), 5% (LM5), 10% (LM10), 15% (LM15) and 20% (LM20). The final weight and specific growth rate were significantly higher in LM15 and LM20 diets fed fish compared to others.

The impact of Achyranthes aspera seeds and leaves supplemented feeds on the survival, growth, immune system and specific genes involved in immunostimulation in Clarias batrachus fry challenged with Aeromonas hydrophila in pond conditions.

The present study was conducted to evaluate the effect of dietary inclusion of Achyranthes aspera seeds and leaves on the immune system of magur Clarias batrachus challenged with Aeromonas hydrophila in pond conditions. Magur fry (0.51 ± 0.

Biochemical composition, transmission and diagnosis of SARS-CoV-2.

Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory infection caused by severe acute respiratory syndrome virus (SARS-CoV-2), a novel human coronavirus. COVID-19 was declared a pandemic by World Health Organization in March 2020 for its continuous and rapid spread worldwide. Rapidly emerging COVID-19 epicenters and mutants of concerns have created mammoth chaos in healthcare sectors across the globe.

Bioaugmentation for remediation of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) contaminated soil using a clay based bioformulation.

Bioaugmentation is an important remediation strategy for hazardous organic compounds. A microcosm study was conducted to evaluate the remediation of soils contaminated with hazardous high explosive, Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) using an eco-friendly bioformulation. Janibacter cremeus, an enriched indigenous soil bacterium isolated from the explosive contaminated site was immobilized in a mixture of calcite and cocopeat for bioaugmentation.

Effect of temperature on food consumption, immune system, antioxidant enzymes, and heat shock protein 70 of Channa punctata (Bloch, 1793).

The impact of water temperature on the physiology of Channa punctata (Bloch, 1793) was evaluated in the present study. Fish were acclimated at 25 ± 1 °C and then exposed at six different temperatures: 10, 15, 20, 25, 30, and 35 °C. C.

Microbial remediation of micro-nano plastics: Current knowledge and future trends.

An alarming rise of micro-nano plastics (MNPs) in environment is currently causing the biggest threat to biotic and abiotic components around the globe. These pollutants, apart from being formed through fragmentation of larger plastic pieces and are also manufactured for commercial usage. MNPs enter agro-ecosystem, wildlife, and human body through the food chain, ingestion or through inhalation, causing blockage in the blood-brain barrier, lower fertility, and behavioural abnormalities among other problems.

Exploring Providencia rettgeri for application to eco-friendly paper based microbial fuel cell.

We report results of the studies relating to improved stability (40 days) of small sized microbial fuel cell (MFC) fabricated using agarose embedded paper-based proton exchange membrane. A fermentative bacterium Providencia rettgeri was isolated from rotten potato slurry and identified by 16S rRNA sequencing. The electroactivity of the bacteria was monitored via chronoamperometric and cyclic voltammetric studies using a three-electrode system which indicated the presence of bacterial redox mediator.

A novel egg shell-based bio formulation for remediation of RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) contaminated soil.

Environmental contamination by secondary explosive has been posing threat to human health and the ecosystem. We investigated the potential of a novel bioformulation developed from poultry waste for the bioremediation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) contaminated soils. Eggshells and additives immobilized with an indigenous explosive degrading microbe Janibacter cremeus were utilized for the development of the wettable powder bioformulation.

Aerobic biodegradation of high explosive hexahydro-1,3,5- trinitro-1,3,5-triazine by Janibacter cremeus isolated from contaminated soil.

Objective: To evaluate the ability of Janibacter cremeus a soil bacterium isolated from explosive contaminated site in degradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and to study enzyme responsible for degradation.

Results: The isolate exhibited 88% degradation of RDX in 30 days of incubation. The biodegradation process followed the first order kinetics.

Effect of light intensity on survival, growth and physiology of rohu, (Cyprinidae) fry.

Light intensity is one of the important environmental factors that have strong influence on larviculture. Culture of fish at high intensity of light generates harmful radicals in the body that can compromise their health and production. The present study aims to evaluate the effect of various light intensities on the physiology of rohu fry.

The study of ameliorative effect of dietary supplementation of vitamin C, vitamin E, and tryptophan on Labeo rohita (Cyprinidae) fry exposed to intense light.

The stress ameliorating effect of dietary supplementation of vitamin C, vitamin E, and tryptophan on rohu Labeo rohita fry was evaluated. Rohu fry (1.1 ± 0.

Validation of growth enhancing, immunostimulatory and disease resistance properties of in fry in pond conditions.

The immunostimulatory and disease resistance properties of herb L. (Amaranthaceae) were evaluated in rohu in pond. Rohu fry (1.

Mass Production of and Its Amino Acid and Fatty Acid Profiles.

The surface floating duckweed (Lemnaceae) is a potential ingredient to replace the application of fish-meal in the aqua-feed. The culture technique of the duckweed was standardized in outdoor tanks and then applied in the pond. Three consecutive experiments were conducted in tanks (1.

In vitro digestibility study of some plant protein sources as aquafeed for carps Labeo rohita and Cyprinus carpio using pH-Stat method.

Aquaculture, as a promising food industry, is expected to meet the demand for quality food from the increasing human population. As the diet is critical for feeding farm fish, such a faster growth in the industry is destined to create stress in the fishmeal market to supply diets to the tune. In this context, here, we studied the protein content of 20 plant ingredients, including aquatic weeds, cereals, pulses and oil-cakes using micro-Kjeldahl method and evaluated in vitro digestibility of these ingredients for rohu Labeo rohita and common carp Cyprinus carpio using pH-Stat method.