Publications by authors named "Jahong Koo"
Article Synopsis
- - The rise of obesity and overweight, particularly among children and adolescents, is a pressing societal concern that hasn't been effectively addressed despite known risk factors.
- - This study investigates the impact of environmental nanoplastic pollutants, specifically from polystyrene and polypropylene, on weight gain in mouse offspring whose mothers were exposed to these substances during pregnancy and breastfeeding.
- - Findings reveal that the exposure to nanoplastics leads to abnormal weight gain in offspring, linked to changes in maternal breast milk's lipid composition and gut microbiota in the young mice, suggesting that these pollutants can contribute to obesity in childhood.
As global plastic production continues to grow, microplastics released from a massive quantity of plastic wastes have become a critical environmental concern. These microplastic particles are found in a wide range of living organisms in a diverse array of ecosystems. In this study, we investigated the biological effects of polystyrene nanoplastic (PSNP) on development of the central nervous system using cultured neural stem cells (NSCs) and mice exposed to PSNP during developmental stages.
View Article and Find Full Text PDFIntellectual disability (ID) is a neurodevelopmental disorder defined by below-average intelligence (intelligence quotient of <70) accompanied by adaptive behavior deficits. Defects in the functions of neural stem cells during brain development are closely linked to the pathogenesis of ID. To understand the molecular etiology of ID, we examined neural stem cells from individuals with Duchenne muscular dystrophy (DMD), a genetic disorder in which approximately one-third of the patients exhibit ID.
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