We propose a simple model for chromatin organization based on the interaction of the chromatin fibers with lamin proteins along the nuclear membrane. Lamin proteins are known to be a major factor that influences chromatin organization and hence gene expression in the cells. We provide a quantitative understanding of lamin-associated chromatin organization in a crowded macromolecular environment by systematically varying the heteropolymer segment distribution and the strength of the lamin-chromatin attractive interaction.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
December 2014
In the rotational sandpile model, either the clockwise or the anticlockwise toppling rule is assigned to all the lattice sites. It has all the features of a stochastic sandpile model but belongs to a different universality class than the Manna class. A crossover from rotational to Manna universality class is studied by constructing a random rotational sandpile model and assigning randomly clockwise and anticlockwise rotational toppling rules to the lattice sites.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
December 2008
Invasion of a sticky random solid by an aqueous solution is modeled through a chemical reaction. In this reaction, the solid elements dissolve in the solution and redeposit back on the rough interface. A self-established potential gradient (SEPG) in the binding energy of the solid is developed spontaneously and the system gets phase separated into "hard" and "soft" solids.
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