Henoch-Schonlein purpura in children. Influence of age on the incidence of nephritis and arthritis.

Objective: To assess the epidemiological, clinical, and laboratory findings in children affected with Henoch-Schonlein purpura HSP, and to analyze the influence of age on the incidence of nephritis and arthritis.

Methods: This is a retrospective study of the case records of all patients admitted to Prince Rahmah Hospital, Irbid, Jordan with HSP from September 1997 to December 2006, and to King Abdullah University Hospital, Irbid, Jordan from August 2005 to December 2006.

Results: The clinical manifestations included purpura in 100% of the 68 patients, arthritis in 75%, and nephritis in 29%.

Tubulo-interstitial nephritis and uveitis syndrome in a 6-year-old boy: case report.

A 6-year-old boy presented with a 4-month history of anorexia, weight loss and fatigue and was found to have tubulo-interstitial nephritis and uveitis (TINU) syndrome. After 2 months of corticosteroid therapy, resolution of the uveitis was almost complete but renal function showed only partial improvement. He was still in renal failure 6 months after diagnosis, but there was no relapse of the uveitis.