Publications by authors named "Jahan Yousefian"
Article Synopsis
- The small GTPases Rab5 and Rab7 play key roles in forming and maturing endosomes, with Rab conversion being vital for later steps like fusion with lysosomes.
- Recent studies highlight the Sand1/Mon1 protein family as important for this process, specifically focusing on the Drosophila Dmon1 ortholog.
- Loss of Dmon1 function leads to enlarged endosomes with disrupted Rab7 association, retaining Notch and other proteins without causing expected overactivation signaling, suggesting alternative regulatory mechanisms.
