Publications by authors named "Jagpreet Singh"

Plant-derived carbon dots (P-CDs) are gaining attention in environmental remediation due to their cost-effectiveness, availability, and lower toxicity compared with chemically synthesized carbon dots. This review comprehensively examines the recent advancements in the synthesis and application of P-CDs, with a particular emphasis on their efficacy in the sensing of heavy metals, which are among the most pervasive environmental contaminants. A detailed comparative analysis is presented by evaluating the performance of P-CDs against their chemically synthesized counterparts based on key parameters, such as optimal operating conditions and detection limits.

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The emergence and spread of antibiotic-resistant (AR) bacterial strains and biofilm-associated diseases have heightened concerns about exploring alternative bactericidal methods. The WHO estimates that at least 700 000 deaths yearly are attributable to antimicrobial resistance, and that number could increase to 10 million annual deaths by 2050 if appropriate measures are not taken. Therefore, the increasing threat of AR bacteria and biofilm-related infections has created an urgent demand for scientific research to identify novel antimicrobial therapies.

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A slight variation in ecological milieu of plants, like drought, heavy metal toxicity, abrupt changes in temperature, flood, and salt stress disturbs the usual homeostasis or metabolism in plants. Among these stresses, salinity stress is particularly detrimental to the plants, leading to toxic effects and reduce crop productivity. In a saline environment, the accumulation of sodium and chloride ions up to toxic levels significantly correlates with intracellular osmotic pressure, and can result in morphological, physiological, and molecular alterations in plants.

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The surging demand for eco-friendly nanomaterial synthesis has spurred the emergence of green approaches for synthesizing carbon dots (CDs). These methods utilized natural carbon sources, such as different kind of waste for CDs synthesis, underscoring their significance in waste management and circular economy initiatives. Furthermore, the properties of CDs can be tailored by their functionalization with different materials, enabling their versatile utilization in diverse scientific domains.

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Unlabelled: Phenotypic plasticity is a recognized mechanism driving therapeutic resistance in prostate cancer (PCa) patients. While underlying molecular causations driving phenotypic plasticity have been identified, therapeutic success is yet to be achieved. To identify putative master regulator transcription factors (MR-TF) driving phenotypic plasticity in PCa, this work utilized a multiomic approach using genetically engineered mouse models of prostate cancer combined with patient data to identify MYBL2 as a significantly enriched transcription factor in PCa exhibiting phenotypic plasticity.

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The waste management and water purification are daunting environmental challenges. Biochar, a carbonaceous material prepared from diverse organic waste (agricultural, household residues and municipal sewage sludge) has garnered substantial attention due to its excellent attributes, including carbon content, cation exchange efficacy, ample specific surface area, and structural robustness. Thus, the present review comprehensively analyzes bio waste-derived biochar with a particular emphasis on water remediation applications.

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In today's era, nanoparticles (NPs) have become an integral part of human life, finding extensive applications in various fields of science, pharmacy, medicine, industry, electronics, and communication. The increasing popularity of NP usage worldwide is a testament to their tremendous potential. However, the widespread deployment of NPs unavoidably leads to their release into the environmental matrices, resulting in persistence in ecosystems and bioaccumulation in organisms.

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Toxic dyes in water bodies and bacterial pathogens pose serious global challenges to human health and the environment. Zinc oxide nanoparticles (ZnO NPs) demonstrate remarkable photocatalytic and antibacterial potency against reactive dyes and bacterial strains. In this work, PVP-ZnO NPs have been prepared via the co-precipitation method using polyvinylpyrrolidone (PVP) as a surfactant.

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Environmentally benign synthesis of nanocomposite, a pivotal facet of nanotechnology, and gaining prominence due to the increasing demand for facile, sustainable, and safe synthesis methods. The present research reports an facile/cost-effective method for the preparation of carbon dots (CDs) and carbon dot silver nanocomposites ( CD@AgNCs) via a hydrothermal treatment of peanut shells. The well-dispersed and spherical CDs with an average diameter of 5-6 nm were obtained and further employed for the preparation of CD@AgNCs.

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The increase of microplastic contamination in Vietnam is a growing concern due to various domestic, agricultural, and industrial activities. The use of plastic mulch and sludge application in agricultural farmland, textile production, daily consumer items, cleaning agents, and health/personal care products contribute significantly to the increasing microplastic pollution in the aquatic ecosystem. The concentration of microplastics reported in surface water ranged from 0.

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The development of a country is inseparable from the material guarantee mainly based on energy, but energy is limited, which may restrict the sustainable development of the country. It is very necessary to accelerate the adoption of programs aimed at switching non-renewable energy sources to ones that are, and giving priority to improving renewable energy consumption and storage capabilities. From the experience of the G7 economies, the development of renewable energy (RE) is inevitable and urgent.

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The alarming impact of antibiotic resistance sparked the quest for complementary treatments to overcome the confrontation over resistant pathogens. Metallic nanoparticles, especially silver nanoparticles (Ag NPs) have gained a much attention because of their remarkable biological characteristics. Moreover, their medicinal properties can be enhanced by preparing the composites with other materials.

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Global waste production is anticipated reach to 2.59 billion tons in 2030, thus accentuating issues of environmental pollution and health security. 37 % of waste is landfilled, 33 % is discharged or burned in open areas, and only 13.

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The viral diseases encouraged scientific community to evaluate the natural antiviral bioactive components rather than protease inhibitors, harmful organic molecules or nucleic acid analogues. For this purpose, medicinal plants have been gaining tremendous importance in the field of attenuating the various kinds of infectious and non-infectious diseases. Most of the commonly used medicines contains the bioactive components/phytoconstituents that are generally extracted from medicinal plants.

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Chromium (Cr) is reported to be hazardous to environmental components and surrounding biota when levels exceed allowable thresholds. As Cr is extensively utilized in different industries, thereby comprehensively studied for its toxicity. Along with Cr, the applications of nano-Cr or chromium oxide nanoparticles (CrO-NPs) are also expanding; however, the literature is scarce or limited on their phytotoxicity.

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Emerging organic pollutants (EOPs) are a category of pollutants that are relatively new to the environment and recently garnered a lot of attention. The majority of EOPs includes endocrine-disrupting chemicals (EDCs), antibiotic resistance genes (ARGs), pesticides, dyes and pharmaceutical and personal care products (PPCPs). Exposure to contaminated water has been linked to an increase in incidences of malnutrition, intrauterine growth retardation, respiratory illnesses, liver malfunctions, eye and skin diseases, and fatalities.

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It has been a never-ending quest to design a safe, cost-effective, and environmentally acceptable technology for eliminating contaminants from water and countering antibiotic resistance. Herein, a waste leaf extract from the abundant and renewable plant, Brassica oleracea var. gongylodes, is introduced as a cost-effective and sustainable means to generate gold (Au) and Au@Ag core-shell nanoparticles (NPs).

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Groundwater pollution is mostly caused by overuse of fertilizers, pesticides, contemporary agricultural practices, anthropogenic activities, home waste disposal, and the rapid expansion of the chemical industry. Drinking tainted water on a regular basis can have detrimental consequences on human health as well on environment. Nanoparticles (NPs) based contaminants alleviation strategy found to be most efficient, cost-effective and reliable.

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The rapid growth of pollutants, both biological and non-biological, puts environmental systems in jeopardy. In view of this, the current study demonstrates the synthesis of undoped and Cobalt-doped zinc oxide nanoparticles (Co doped ZnO NPs) via co-precipitation method. The confirmation of incorporation of the Co dopant into ZnO NPs was verified through various spectroscopic and microscopic techniques.

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The development of a non-malignant and sustainable treatment approach for eradicating mephitic organic dyes from freshwater resources is a daunting task. In a similar vein, the current work investigates the mitigation of methylene blue (MB) dye utilizing titanium dioxide nanoparticles (CS-TiO NPs) synthesized using (bhang) leaf extract via a greener approach. The CS-TiO NPs are well characterized through XRD, FE-SEM, HR-TEM, UV-Vis spectroscopy, FTIR spectroscopy, and EDS spectroscopy.

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Silver nanoparticles play a significant role in biomedical sciences due to their unique properties allowing for their use as an effective sensing and remediation platform Herein, the green synthesis of silver nanostructures (Ag NSs), prepared via aqueous extract of waste leaves in the presence of silver nitrate solution (10 M), is reported. The Ag NSs are fully characterized and their efficacy with respect to 4-nitrophenol reduction, glucose sensing, and microbes is determined. Visually, the color of silver nitrate containing solution altered from colorless to yellowish, then reddish grey, confirming the formation of Ag NSs.

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Article Synopsis
  • * The review focuses on recent advancements in biological methods for synthesizing Ag NPs and examines their antimicrobial mechanisms of action.
  • * It also touches on the potential short and long-term toxic effects of Ag NPs on animals, the environment, and human health, while summarizing the current research landscape and future challenges in using biologically mediated Ag-nanostructures to tackle AMR.
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Nanotechnology is a fast-expanding area with a wide range of applications in science, engineering, health, pharmacy, and other fields. Nanoparticles (NPs) are frequently prepared via a variety of physical and chemical processes. Simpler, sustainable, and cost-effective green synthesis technologies have recently been developed.

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Increases in biological and non-biological pollutants pose a significant threat to environmental systems. In an effort to develop an effective means to treat such pollutants, the use of Phaseolus vulgaris (kidney beans) as reducing and capping agents is proposed for the green synthesis of highly stable silver nanoparticles (AgNPs) with a face-centered cubic (fcc) crystalline structure (size range: 10-20 nm). The potent role of the resulting AgNPs was found as triple platforms (photocatalyst, catalyst, and antimicrobial disinfectant).

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