Severe Thrombocytopenia in Dengue Fever and Vitamin B12 Level.

Objective: To document correlation between vitamin B12 deficiency and severity of thrombocytopenia, platelate recovery and duration of hospital stay in dengue fever patients.

Methods: This prospective observationl study was done in dengue fever patient with severe prolonged thrombocytopenia (<20,000 µl and > 2 days duration). Patient with underlying malignancy, hematological disorders, septicemia, or use of any drug which may cause thrombocytopenia, were excluded.