Publications by authors named "Jagat Bhushan"

Aim: The aim of the study was to assess and evaluate the antimicrobial effectiveness of chitosan nanoparticles (CSNPs) with calcium hydroxide in the elimination of .

Materials And Methods: Using the broth microdilution method, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of calcium hydroxide and CSNPs were measured. The antibiofilm effect of calcium hydroxide and CSNPs against biofilm was qualitatively analyzed using a crystal violet assay.

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Article Synopsis
  • Curcumin and its nanoformulation, nanocurcumin, are studied for their antibacterial properties in endodontics, particularly against E. coli.
  • The study uses gutta-percha cones coated with curcumin and nanocurcumin and assesses their antibacterial effectiveness using scanning electron microscopy.
  • Results show that gutta-percha cones coated with nanocurcumin have the strongest antibacterial activity, outperforming both uncoated and curcumin-coated cones.
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Background: Endodontic infections have been clearly described as biofilm-mediated infections. Bacteria and their by-products have been known to cause these infections. With the introduction of new drugs and the use of nanoparticles in recent times, there has been a significant reduction in the bacterial load in endodontic infections.

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Introduction: During dental procedures, dental professionals as well as patients are exposed to pathogens and toxic substances, which may be transmitted through direct or indirect contact. Their clothing is visibly soiled during the procedures. Their hands can serve as vectors for the transmission of pathogens.

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Background: The persistence of microorganisms in root canal system is pivotal factor pertinent to endodontic failure. Even if you meet the highest technical and asepsis standards and also minimize the procedural errors, failures result. The rapidly increasing antibiotic resistance among these bacteria and the adverse effects of these antibiotics along with their toxicity are the main situations indicating the utmost urgent requirement of a safe, effective, natural phytochemical like curcumin with tremendous medicinal potential.

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Background: Perforation repair materials should have excellent sealing ability and dislodgement resistance. While several materials have been employed for perforation repair, newer calcium-silicate materials, such as Biodentine and TheraCal LC, have shown promising outcomes.

Aims: This study aimed to evaluate the effect of different irrigants on the dislodgement resistance of Biodentine and TheraCal LC when used for perforation repair in simulated conditions.

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Background: Nanocurcumin has antimicrobial properties and it is to be tested as a coating on gutta-percha against .

Aim: To evaluate the antimicrobial efficacy of nanocurcumin-coated gutta-percha against E. faecalis in comparison with conventional gutta-percha.

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Aim: This study aims to detect the dentinal defects associated with different irrigants during biomechanical preparation using rotary nickel-titanium (Ni-Ti) files (Hyflex CM).

Materials And Methods: For the study, 120 extracted mandibular incisors were taken. Depending on the irrigant used, teeth were divided into six groups ( = 20).

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Aim: The main aim of the study is to compare the antibacterial effect of Silver nanoparticle gel alone and combination of silver nanoparticle gel with various medicaments.

Materials And Methods: Intracanal dressings: Group 1 -Silver Nanocure gel, Group 2 - Silver Nanocure gel+ Cavisept gel(1:1),Group 3- Silver Nanocure gel+ Aveu-Cal gel(1:1) ,Group 4 - Silver Nanocure gel +Cavisept gel +Aveu-Cal gel(1:1:1) were taken on a culture plate inoculated with . Antibacterial activity was assessed using Agar diffusion test and results were noted as diameter of growth inhibition zone.

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