Publications by authors named "Jagannatha Rao Kosagisharaf"
Article Synopsis
- The review focuses on toxoplasmosis rates in Panama and Colombia, analyzing data on seroprevalence and risk factors.
- Studies showed seroprevalence in Ciudad de Panamá ranged from 22% to 44%, with higher rates linked to poverty and closeness to water.
- Heat maps and mathematical models were created to pinpoint areas that need targeted healthcare campaigns for congenital toxoplasmosis and infections.
Article Synopsis
- The purpose of the review was to develop and assess educational materials aimed at reducing disease burdens from infections in Panama, Colombia, and the USA.
- Recent findings indicate that educational programs in these countries have not yet been evaluated for their effectiveness, despite being implemented for various demographics like high school students and pregnant women.
- The summary highlights that these educational materials have shown short-term benefits in disseminating information, with future goals focusing on conducting long-term studies, updating materials based on new research, and increasing access to these resources for broader public health impact.
Alzheimer's disease (AD) is a complex neurodegenerative disorder involving heterogenous pathophysiological characteristics, which has become a challenge to therapeutics. The major pathophysiology of AD comprises amyloid-β (Aβ), tau, oxidative stress, and apoptosis. Recent studies indicate the significance of Triggering receptor expressed on myeloid cells 2 (TREM2) and its mutant variants in AD.
View Article and Find Full Text PDFPurpose Of Review: Review building of programs to eliminate infections.
Recent Findings: Morbidity and mortality from toxoplasmosis led to programs in USA, Panama, and Colombia to facilitate understanding, treatment, prevention, and regional resources, incorporating student work.
Summary: Studies foundational for building recent, regional approaches/programs are reviewed.
Article Synopsis
- The review discusses international efforts to create a global public health initiative for toxoplasmosis, aiming to enhance maternal and child health by preventing and treating the disease.
- Recent findings indicate that some countries are making progress in eliminating toxoplasmosis but face significant challenges.
- Key issues include the high costs and inaccessibility of diagnostic tests and treatment, especially for marginalized communities, as well as delays in essential medical procedures and insurance processes.
Early in the SARS-CoV-2 pandemic, many national public health authorities implemented non-pharmaceutical interventions to mitigate disease outbreaks. Panamá established mandatory mask use two months after its first documented case. Initial compliance was high, but diverse masks were used in public areas.
View Article and Find Full Text PDFDNA stability and conformation are important in the life cycle of an organism. The DNA instability is postulated to be one of the risk factors for neuronal death in neurodegenerative disorders. Among all other risk factors, amyloid is one of the most important risk factor for neurodegeneration.
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