Convolution neural network based infection transmission analysis on Covid-19 using GIS and Covid data materials.

Towards the improvement of predicting and analyzing the infection transmission, a novel CNN (Convolution Neural Network) based Covid Infection Transmission Analysis (CNN-CITA) is presented in this article. The method works based on both GIS data set and the Covid data set. The method reads all the data from the data sets.

A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in medicinal chemistry research.

The spiro[chromane-2,4'-piperidine]-4(3H)-one is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents. This review demonstrated an impressive progress in syntheses of spiro[chromane-2,4'-piperidine]-4(3H)-one-derived compoundsin the recent years and focuses on features of their biological relevance's.

MgN-assisted one-pot synthesis of 1,3-disubstituted imidazo[1,5-]pyridine.

A novel MgN-assisted one-pot annulation strategy has been developed cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-]pyridines exclusively with an exellent yield.

Remarkable anti-breast cancer activity of ferrocene tagged multi-functionalized 1,4-dihydropyrimidines.

A novel series of ferrocene tagged multi-functionalized 1,4-dihydropyrimidines is synthesized by base catalyzed cyclocondensation between ferrocenyl chalcones and amidines. The structures of synthesized compounds were established on the basis of (1)H NMR, (13)C NMR, FTIR spectroscopy as well as by mass spectrometry. The compounds were evaluated for in vitro anticancer activity.