Publications by authors named "Jafit Ting"
Background: Cambodia strives to eliminate all species of human malaria by 2025, requiring that foci among forest-exposed populations in remote settings be addressed. This study explores malaria risks amongst forest-exposed groups in Mondulkiri and Kampong Speu Provinces, Cambodia as part of a multi-stage study on novel mosquito bite prevention tools (Project BITE).
Methods: A serial cross-sectional survey explored the demographics, housing structure openness, mosquito bite prevention habits, and protection from malaria amongst three target groups: forest goers who work in the forest, forest dwellers who live in the forest, and forest rangers who patrol forested regions.
Background: Cambodia strives to eliminate all species of human malaria by 2025, requiring that foci among forest-exposed populations in remote settings be addressed. This study explores malaria risk factors amongst forest-exposed groups in Mondulkiri and Kampong Speu Provinces, Cambodia as part of a multi-stage study on novel bite prevention tools (Project BITE).
Methods: A serial cross-sectional survey explored the demographics, housing structure openness, mosquito bite prevention habits, and gaps in protection amongst three target groups: forest goers who work in the forest, forest dwellers who live in the forest, and forest rangers who patrol forested regions.
Myocardial bridging (MB) is a congenital coronary artery anomaly and an important cause of angina. The genetic basis of MB is currently unknown. This study used a whole-exome sequencing technique and analyzed genotypic differences.
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- * A study involving whole-exome sequencing of 11 Taiwanese patients with severe AIS identified over 200 potential rare genetic variants, but most were unique to single individuals.
- * Key genes linked to AIS were pinpointed, with one pathogenic variant shared among 35% of patients, indicating these genes play critical roles in the condition's development.
Marfan syndrome (MFS) is a rare disease that affects connective tissue, which causes abnormalities in several organ systems including the heart, eyes, bones, and joints. The autosomal dominant disorder was found to be strongly associated with , , and mutations. Although multiple genetic mutations have been reported, data from Asian populations are still limited.
View Article and Find Full Text PDFAsthma is a common and heterogeneous disease characterized by chronic airway inflammation. Currently, the two main types of asthma medicines are inhaled corticosteroids and long-acting β2-adrenoceptor agonists (LABAs). In addition, biological drugs provide another therapeutic option, especially for patients with severe asthma.
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- Atopic Dermatitis (AD) is a chronic skin condition with few effective treatments available, mainly relying on topical corticosteroids and antibiotics.
- The study utilized gene network and genomic analyses to identify and prioritize 94 risk genes associated with AD, leading to the discovery of 27 biological risk genes linked to 76 potential drug targets.
- Among the findings, 25 drug target genes related to 53 drugs were identified, including dupilumab (approved for AD), and ten other potentially effective drugs like filgotinub and various monoclonal antibodies were highlighted for further research.