Early Patching Behaviors that Improve the Chances of Good Visual Acuity in Children Treated for Unilateral Congenital Cataract.

Objective: Achieving near normal vision following unilateral congenital cataract surgery is possible but requires early surgery, optical correction and consistent patching. Patching is often challenging for children and their caregivers. The goal of these analyses is to examine the association between reported consistency in patching during the first year after surgery and visual acuity.

The Prevalence of Obesity is Increased in Adolescents with Amblyopia: An Analysis of National Health and Nutrition Examination Survey Data.

Amblyopia is the most common cause of vision loss in children. Amblyopia has been associated with impaired depth perception but little attention has been paid to the extent to which amblyopia increases the risk of obesity. Public-use data from the 1999-2008 National Health and Nutrition Examination Survey were used.

Is Patching after Age 4 Beneficial for Children Born with a Unilateral Congenital Cataract?

Purpose: The goal of these analyses is to provide evidence that can help parents and healthcare providers determine whether or not to continue occlusion therapy once a reliable measure of optotype acuity can be obtained in children who are born with a unilateral congenital cataract.

Design: Data from the Infant Aphakia Treatment Study (IATS) are used in a cohort design.

Participants: A total of 105 children who participated in the IATS and did not have a vision-threatening adverse event.

Patching in Children With Unilateral Congenital Cataract and Child Functioning and Parenting Stress.

Importance: Parents may be concerned about the adverse outcomes of occlusion therapy in children treated for unilateral congenital cataract (UCC).

Objective: To determine whether occlusion therapy in children treated for UCC with poor visual outcomes is negatively associated with poorer child and/or family functioning.

Design, Setting, And Participants: This cohort study was conducted in 2023 using data collected between 2006 and 2016 in the Infant Aphakia Treatment Study (IATS).

Exploring Disability as a Determinant of Girl Child Marriage in Fragile States: A Multicountry Analysis.

Purpose: Fragile states are countries characterized by poverty, conflict, political instability, insecurity, and disaster. In such settings, there are high levels of disability and women and girls are disproportionately impacted by violence. Despite the 2030 Sustainable Development Goal's call for both the elimination of violence against women and girls and disability-disaggregated data, few studies have investigated how disability may be associated with girl child marriage (GCM) and how these two factors impact intimate partner violence (IPV).

Disability and intimate partner violence in fragile states: A multi-country analysis.

The 2030 Sustainable Development Goals call for both the elimination of violence against women and girls and disability-disaggregated data. However, few population-based, multi-country studies have examined how disability impacts intimate partner violence (IPV) in fragile settings. Demographic and Health Survey data from five countries (Pakistan, Timor-Leste, Mali, Uganda, and Haiti) were pooled and analyzed to assess the relationship between disability and IPV ( = 22,984).

The association between women's disability and acceptance towards intimate partner violence among women and their male partners: A multi-country analysis.

Objective: To examine whether disabled women are more likely to report accepting attitudes towards intimate partner violence (IPV) than non-disabled women, and whether male partners of disabled women are more likely to accept IPV than male partners of non-disabled women.

Methods: Secondary analysis of nationally representative cross-sectional data from the Demographic Health Survey (DHS) in nine countries. Logistic regression examined the relationship between (1) women's disability and IPV acceptance (n = 114 695) and (2) women's disability and their male partners' IPV acceptance (n = 20 566); pooled and country-specific estimates were calculated.

SUFFICIENT CAUSE INTERACTIONS FOR CATEGORICAL AND ORDINAL OUTCOMES.

The sufficient cause model is extended from binary to categorical and ordinal outcomes to formalize the concept of sufficient cause interaction and synergism in this setting. This extension allows us to derive counterfactual and empirical conditions for detecting the presence of sufficient cause interactions for ordinal and categorical outcomes. Some of these conditions are entirely novel in that they cannot be derived from the sufficient cause model for binary outcomes.

On the identification of individual level pleiotropic, pure direct, and principal stratum direct effects without cross world assumptions.

The analysis of natural direct and principal stratum direct effects has a controversial history in statistics and causal inference as these effects are commonly identified with either untestable cross world independence or graphical assumptions. This article demonstrates that the presence of individual level natural direct and principal stratum direct effects can be identified without cross world independence assumptions. We also define a new type of causal effect, called pleiotropy, that is of interest in genomics, and provide empirical conditions to detect such an effect as well.

Dramatic increase in HIV prevalence after scale-up of antiretroviral treatment.

Objectives: To investigate HIV prevalence trends in a rural South African community after the scale-up of antiretroviral treatment (ART) in 2004.

Methods: We estimated adult HIV prevalence (ages 15-49 years) using data from a large, longitudinal, population-based HIV surveillance in rural KwaZulu-Natal, South Africa, over the period from 2004 (the year when the public-sector ART scale-up started) to 2011. We control for selection effects due to surveillance nonparticipation using multiple imputation.

High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa.

The landmark HIV Prevention Trials Network (HPTN) 052 trial in HIV-discordant couples demonstrated unequivocally that treatment with antiretroviral therapy (ART) substantially lowers the probability of HIV transmission to the HIV-uninfected partner. However, it has been vigorously debated whether substantial population-level reductions in the rate of new HIV infections could be achieved in "real-world" sub-Saharan African settings where stable, cohabiting couples are often not the norm and where considerable operational challenges exist to the successful and sustainable delivery of treatment and care to large numbers of patients. We used data from one of Africa's largest population-based prospective cohort studies (in rural KwaZulu-Natal, South Africa) to follow up a total of 16,667 individuals who were HIV-uninfected at baseline, observing individual HIV seroconversions over the period 2004 to 2011.