Miniaturized Wirelessly Powered and Controlled Implants for Multisite Stimulation.

This paper presents a miniaturized implant with a diameter of only 14 mm, which houses a novel System on Chip (SoC) enabling two voltage level stimulation of up to 16 implants using a single Tx coil. Each implant can operate at a distance of 80 mm in the air through the inductive resonant link. The SoC consumes only 27 W static power and enables two channels with stimulation amplitudes of 1.

Vagus nerve stimulation using a miniaturized wirelessly powered stimulator in pigs.

Neuromodulation of peripheral nerves has been clinically used for a wide range of indications. Wireless and batteryless stimulators offer important capabilities such as no need for reoperation, and extended life compared to their wired counterparts. However, there are challenging trade-offs between the device size and its operating range, which can limit their use.

Subthreshold electrical stimulation as a low power electrical treatment for stroke rehabilitation.

As a promising future treatment for stroke rehabilitation, researchers have developed direct brain stimulation to manipulate the neural excitability. However, there has been less interest in energy consumption and unexpected side effect caused by electrical stimulation to bring functional recovery for stroke rehabilitation. In this study, we propose an engineering approach with subthreshold electrical stimulation (STES) to bring functional recovery.

A 540-[Formula: see text] Duty Controlled RSSI With Current Reusing Technique for Human Body Communication.

An ultra-low-power duty controlled received signal strength indicator (RSSI) is implemented for human body communication (HBC) in 180 nm CMOS technology under 1.5 V supply. The proposed RSSI adopted 3 following key features for low-power consumption; 1) current reusing technique (CR-RSSI) with replica bias circuit and calibration unit, 2) duty controller, and 3) reconfigurable gm-boosting LNA.

Identification and functional assessment of BCRP polymorphisms in a Korean population.

The breast cancer resistance protein (BCRP) is a member of the ATP-binding cassette transporters. The aim of the present study was to identify genetic variants of BCRP in Koreans and to assess the functional consequences of BCRP polymorphisms. Twenty single nucleotide polymorphisms (SNP), including four nonsynonymous SNP, were identified by DNA sequencing of the BCRP gene in 92 Korean subjects.