Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.

Background And Aims: The FibroTest (FT) demonstrated excellent diagnostic performance in the prediction of liver fibrosis in patients with chronic hepatitis B (CHB). Here, we aimed to identify predictors of discordance between FT and liver biopsy (LB) in Asian patients with CHB.

Methods: Consecutive patients with CHB who underwent both LB and FT on the same day between 2007 and 2010 were recruited from three medical institutes.

[Entecavir therapy for patients with hepatitis B virus-related decompensated cirrhosis].

Background/aims: Entecavie (ETV) has a potent antiviral effect and low rates of resistance in hepatitis B virus (HBV) and is the first-line monotherapy in patients with HBV-related decompensated cirrhosis. We evaluated the efficacy of 12 months treatment with ETV and tried to determine predictive factors of response.

Methods: Forty-five consecutive decompensated cirrhotic patients who received ETV (0.