Publications by authors named "Jae E Lee"

FAPbI has emerged as a promising semiconductor for photovoltaic applications offering a suitable bandgap for single-junction cells and high chemical stability. However, device efficiency is negatively affected by intrinsic quantum confinement (QC) effects that manifest as additional peaks in the absorption spectra. Here, we show that aerosol-assisted crystallization is an effective method to improve crystallinity and suppresses regions exhibiting QC in FAPbI.

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Background: The American Heart Association recently introduced a new framework, known as cardiovascular-kidney-metabolic (CKM) syndrome, aimed at the early prevention of cardiovascular disease. However, this syndrome has not been studied extensively outside of the United States. Thus, this study aimed to examine the long-term trends in CKM syndrome and its associated demographic features in South Korea.

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This study aims to classify citizens' intentions to participate in carbon neutrality activities, emphasizing the crucial role of public engagement in achieving sustainability goals amid the climate crisis. The climate crisis has rapidly become one of the most pressing challenges to global sustainable development, with carbon neutrality as a key objective. To understand variations in citizens' willingness to engage in carbon neutrality efforts, we conducted a Latent Class Analysis (LCA) on responses from 800 residents of Cheongju, South Korea, categorizing their willingness to participate in 13 different carbon neutrality activities.

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Purpose: The purpose of this study was to investigate the effects of postoperative complications on long-term survival after laparoscopic surgery for resectable colorectal cancer.

Methods: We retrospectively included 204 patients who underwent laparoscopic surgery for colorectal cancer from January 2016 to June 2020.

Results: Overall, 68 (33.

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Background: Sarcopenia is a condition that poses a significant risk in the older population, with diabetes identified as a risk factor. Recent evidence suggests that GLP-1 RA, commonly used as antidiabetic treatments, may potentially induce sarcopenia. This study aimed to investigate the association between sarcopenia and various antidiabetic drugs, including GLP-1 RAs.

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This study was conducted to investigate whether lysophosphatidic acid (LPA) could improve the development of porcine somatic cell nuclear transfer (SCNT) embryos. Porcine SCNT-derived embryos were cultured in chemically defined polyvinyl alcohol (PVA)-based porcine zygote medium (PZM)-4 without or with LPA, and the development, cell proliferation potential, apoptosis, and expression levels of pluripotent markers were evaluated. LPA significantly increased the rates of cleavage and blastocyst formation compared to those seen in the LPA un-treatment (control) group.

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Objective: The cerebral and spinal venous systems have similar functions but unique anatomical and physiological properties. CSF occupies space in the cranial and spinal vaults, is continuously produced, and has many roles, including maintaining a favorable environment for CNS structures. The influence of the cerebrospinal venous system on CSF dynamics has been theorized since the 1940s.

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Article Synopsis
  • The study analyzes the risks of subsequent primary cancers (SPCs) in cancer survivors, using data from South Korea's health database from 2009 to 2019, focusing on different types of first primary cancers (FPC) considering age and sex.
  • Results showed that out of over 266,000 cancer survivors, there was a 26% lower overall risk of developing SPCs, with variations in risk among different types of FPCs and between men and women.
  • Younger cancer survivors had a higher risk of SPCs compared to older survivors, with specific cancer types like lung and breast cancers being the most common subsequent cancers observed.
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The global challenges posed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have underscored the critical importance of innovative and efficient control systems for addressing future pandemics. The most effective way to control the pandemic is to rapidly suppress the spread of the virus through early detection using a rapid, accurate, and easy-to-use diagnostic platform. In biosensors that use bioprobes, the binding affinity of molecular recognition elements (MREs) is the primary factor determining the dynamic range of the sensing platform.

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  • Health care workers (HCWs) are at a higher risk of COVID-19 infection, leading to this study's evaluation of infection-control measures in a Seoul hospital from 2020 to 2022.
  • Results showed that HCWs had a lower COVID-19 risk compared to the general population, but non-medical service staff and certain other HCWs were identified as high-risk groups.
  • The effectiveness of the COVID-19 booster vaccine was estimated at 55.47%, highlighting the need for targeted vaccination and infection-control efforts for high-risk departments and individuals.
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Background: A infection control nurse (ICN) has played substantial roles in infection control and epidemiology programs in hospitals to protect patients and coworkers during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to explore the association between intention to leave in ICNs and job stress and burnout.

Methods: This cross-sectional study was conducted among ICNs working in hospitals with ≥200 beds in South Korea from October 1 to 22, 2021.

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Metal halide perovskite semiconductors have shown significant potential for use in photovoltaic (PV) devices. While fabrication of perovskite thin films can be achieved through a variety of techniques, thermal vapor deposition is particularly promising, allowing for high-throughput fabrication. However, the ability to control the nucleation and growth of these materials, particularly at the charge-transport layer/perovskite interface, is critical to unlocking the full potential of vapor-deposited perovskite PV.

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  • Metastatic gastric cancer (GC) progression leads to death, but its genomic and evolutionary traits have been underexplored.
  • A study analyzed the whole-exome sequencing of 99 primary and metastatic gastric cancers from 15 patients, revealing differences in chromosomal instability and mutations based on the type of metastasis.
  • The findings suggest that distinct genomic features of metastatic GC are linked to patient survival and highlight the need for genomic assessment of both primary and metastatic tumors.
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  • The study identifies specific gene signature-based subtypes of gastric cancer (GC) that are linked to treatment resistance and poor outcomes, analyzing data from 547 cases.
  • Researchers explored the relationship between these cancer subtypes and the tumor microenvironment using advanced techniques, revealing that some GC cells are in a partial epithelial-mesenchymal transition state.
  • By targeting TGF-β signaling, which they found to drive mesenchymal traits in cancer cells, the study suggests new therapeutic strategies that could reduce resistance to treatment in gastric cancer.
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Accuracy of acceleromyography (AMG) is not be comparable to that of mechanomyography or electromyography (EMG). In particular, the prone position may reduce the accuracy and feasibility of AMG. We developed a new device based on wrist brace to allow free thumb movement and fix the other parts of the hand and wrist.

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Paracavernous dural arteriovenous fistulas (pdAVFs) are extremely rare and can mimic carotid cavernous fistulas (CCFs) in both clinical presentation and imaging characteristics. Access to the venous pouch often presents the greatest challenge in the treatment of pdAVFs. Here we present a novel access technique utilizing an endoscopic endonasal transsphenoidal approach, where we directly puncture the venous pouch under both stereotactic guidance and endoscopic visualization, thereby completely embolizing a pdAVF with no alternate access (video 1).

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Arachnoid cysts of the fourth ventricle are rarely reported. Management options include CSF diversion, cyst fenestration, or cyst excision. Fenestration can be done via open microsurgical technique or endoscopically with or without simultaneous third ventriculostomy; and both rigid and flexible endoscopy have been used successfully.

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Previously, we reported that an inverse agonist of estrogen-related receptor gamma (ERRγ), GSK5182, enhances sodium iodide (Na/I) symporter (NIS) function through mitogen-activated protein (MAP) kinase signaling in anaplastic thyroid cancer cells. This finding helped us to further investigate the effects of GSK5182 on NIS function in papillary thyroid cancer (PTC) refractory to radioactive iodine (RAI) therapy. Herein, we report the effects of ERRγ on the regulation of NIS function in RAI-resistant PTC cells using GSK5182.

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Objective: Genetic alterations are increasingly recognized as etiologic factors linked to the pathogenesis and development of cerebrovascular anomalies. Their identification allows for advanced screening and targeted therapeutic approaches. The authors aimed to describe the role of a collaborative approach to care and genetic testing in pediatric patients with neurovascular anomalies, with the objectives of identifying what genetic testing recommendations were made, the yield of genetic testing, and the implications for familial screening and management at present and in the future.

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This study aimed to identify factors influencing disaster preparedness capability, measure and compare the relative importance of evaluation indicators of preparedness capability in a rainstorm disaster, and analyze the impact of these factors on disaster preparedness so as to improve disaster preparedness capability. The evaluation model was proposed by constructing the target level (the first level) as an indicator system; this was divided into four indicators (the second level): planning, organization, equipment, and education and exercise, and 14 tertiary evaluation indicators (the third level). The validity of the evaluation index system was demonstrated, and the weight of each level was calculated using the Analytic Hierarchical Process and expert survey methods, taking the example of the Zhengzhou "7.

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A middle-aged patient presented with right-sided chemosis, exophthalmos, and progressive visual loss. Digital subtraction angiography revealed a type D carotid-cavernous fistula (CCF). Transarterial embolization through the internal maxillary artery was unsuccessful, and there was no venous access to the CCF.

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A structural protein of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), nucleocapsid (N) protein is phosphorylated by glycogen synthase kinase (GSK)-3 on the serine/arginine (SR) rich motif located in disordered regions. Although phosphorylation by GSK-3β constitutes a critical event for viral replication, the molecular mechanism underlying N phosphorylation is not well understood. In this study, we found the putative alpha-helix L/FxxxL/AxxRL motif known as the GSK-3 interacting domain (GID), found in many endogenous GSK-3β binding proteins, such as Axins, FRATs, WWOX, and GSKIP.

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