Neurotoxic effect of dermally applied chlorpyrifos and cypermethrin. Reversibility of changes.

Nurelle D 550 EC preparation (Dow Elanco, USA) was applied in the study. The contents of biologically active substances in 1l of the preparation was: 500 g chlorpyrifos and 50 g of cypermethrin. The experimental studies were conducted on 4 groups of rats (2 control - 10 animals in each group, and 2 experimental - 40 animals in each group).

Toxoplasmosis in rabbits confirmed by strain isolation: a potential risk of infection among agricultural workers.

The presence of anti-Toxoplasma gondii IgG antibodies in a high titer of 1:8,000 was found in 2 out of 9 examined rabbits (22.2%), kept on a farm where cases of human toxoplasmosis were noted. A virulent Toxoplasma gondii strain was isolated in mice from the brain of a seropositive rabbit that showed clinical signs of disease: apathy, weight loss, skin lesions.

Dermal and oral toxicity of malathion in rats.

The aim of the study was the evaluation of dermal and oral toxicity of malathion based on the results of histopathologic and ultrastructural tests. The standard of the pesticide - IPO 460 Malathion was used in the study. The preparation was suspended in oil emulsion.

Comparison of histological and ultrastructural changes in mice organs after supplementation with inorganic and organic selenium.

Two organic compounds of selenium, 4-o-totyl-selenosemicarbazide p-chlorobenzoic acid (chain compound) produced at the Chemistry Department of the University Medical School in Lublin, and one inorganic compound of sodium IV selenite (Na(2)SeO(3)) were used. The preparations were used per os in doses of 1 mg/kg body weight and 0.5 mg/kg body weight.

Distribution of dermally absorbed 14C DDT in the organs of Wistar rats.

The aim of study was evaluation of the concentration of dermally applied (14)C DDT in the organs of rats, and evaluation of histological and ultrastructural changes after the dermal application of unlabelled DDT standard in the organs of rats, in which the presence of this pesticide was determined by the radio-isotopic method. (14)C DDT of radiochemical purity of 97% was applied in the study. The activity of the preparation per 1 cm(2) of the tail skin was 22.

Chlorfenvinphos Dermal Absorption in Rats: Histological and Ultrastructural Changes in the Skin and Internal Organs.

We studied the effect of chlorfenvinphos dermal absorption on the morphological picture of blood, on the histological and fine structure of tail skin, and on the histological structure of internal organs (lungs, heart, liver, spleen, and kidney) of rats. This study was conducted on 25 white Wistar rats, the tail skin of which was-or was not-hydrated before exposure. Rat tails were soaked in 0.