The influence of gene presence/absence polymorphisms on the development of periodontal disease in smokers and non-smokers.

Introduction: Periodontal diseases are highly prevalent inflammatory, multifactorial diseases. Smoking is one of the most important environmental risk factors for the development and severity of periodontal disease. Killer cell immunoglobulin-like receptors (KIRs) are members of the immunoglobulin (Ig) superfamily and play an essential role in the regulation of NK cell activity, allowing natural killer (NK) cells to sense and respond to human leukocyte antigen (HLA) class I.

A comparison of the periodontal status in patients with type 2 diabetes based on glycated haemoglobin levels and other risk factors.

Purpose: The aim of this study was to compare the periodontal status in patients with type 2 diabetes based on glycated haemoglobin levels and other risk factors.

Material/methods: 75 patients with DM2 were grouped according to glycemic control: 40 subjects with HbA1c<7.0% and 35 subjects with HbA1c≥7.

Are KIR genes associated with clinical parameters in the course of periodontitis?

Introduction: Periodontitis is a common chronic inflammatory disease. It seems that natural killer (NK) cells play a role in the pathogenesis of periodontitis. KIRs are a family of inhibitory or activating receptors expressed on the surfaces of NK cells and some subpopulations of T lymphocytes.

[The effect of tobacco smoke on the course and severity of inflammation in periodontal tissues].

Introduction: The spreading habit of smoking and the characteristic effects of components of tobacco smoke make nicotinism the main etiologic factor of many diseases and the factor which modifies their course. Inflammation of periodontal tissues is included here. The aim of this work was to investigate the effect of tobacco smoke on some clinical parameters of periodontal tissues in adults, habitual smokers of tobacco, who reported with chronic periodontitis, and whose general state of health was otherwise normal.

[Anaerobic bacteria of periodontal pockets in course of periodontitis and premature labor].

The aim of the study is was to evaluate anaerobic periodontal mikrobes in 120 postpartum mothers. Group I consisted of mothers with a birth weight of less than 2,500g and gestational age < 37 weeks. Group II included mothers with normal birth weight infants.

Matrix metalloproteinase-1 gene polymorphism in renal transplant patients with and without gingival enlargement.

Background: Gingival enlargement frequently occurs in transplant patients receiving immunosuppressive drugs. It was hypothesized that gingival enlargement associated with cyclosporin use results in a disturbance of the homeostatic balance, which is characterized by an increase in the number of fibroblasts and volume of the extracellular matrix. Matrix metalloproteinase (MMP) serves as an initiator of extracellular matrix destruction.