Ozone Exposure Controls Oxidative Stress and the Inflammatory Process of Hepatocytes in Murine Models.

(1) Background: Ozone exposure is a promising tool for treating liver damage since it is known to control the release of free radicals and increase the expression of antioxidant enzymes. The objective is to investigate the main intracellular pathways activated after exposure to ozone, considering the dosage of antioxidant enzymes and markers of oxidative stress. (2) Methods: This systematic review was performed based on the PRISMA guidelines and using a structured search in MEDLINE (PubMed), Scopus, and Web of Science.

Phenolic-rich extract of attenuates gastric lesions induced in experimental models through inhibiting oxidative stress, modulating inflammatory markers and a cytoprotective effect.

(Cactaceae), popularly known as "palma" or "palma doce", is from Mexico, but it was widely introduced in Brazil through crops. It has been used as food and in traditional medicine and is a good source of phenolic compounds. In this study the phytochemical profile and gastroprotective activity of phenolic-rich extract of in acute gastric lesion models induced by ethanol and indomethacin were evaluated.

Gel formulated with leaf extract promotes skin wound healing by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals.

(Crassulaceae) is used in traditional medicine for treating skin wounds. In our previous study, a topical gel containing aqueous leaf extract showed a preclinical anti-inflammatory effect in acute edema models. In continuation, the present study aims to evaluate the phytochemical content and the stability of a formulation in gel containing aqueous leaf extract and its healing properties and mechanism of action through an experimental model of induction of skin wounds in rats and assays.