Publications by authors named "Jacqui Agostinello"

Article Synopsis
  • The Early and Intensive Motor Training Trial aims to evaluate if 10 weeks of high-dosage motor training can enhance neurological recovery in individuals with spinal cord injuries.
  • This study will involve 220 participants across various European countries and Australia, focusing on how the training impacts recovery outcomes.
  • The research will utilize a process evaluation framework to analyze factors that may influence the effectiveness and future implementation of the intervention, while also ensuring ethical standards are upheld throughout the trial.
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Study Design: Protocol for a multi-centre randomised controlled trial (the SCI-MT trial).

Objectives: To determine whether 10 weeks of intensive motor training enhances neurological recovery in people with recent spinal cord injury (SCI).

Setting: Fifteen spinal injury units in Australia, Scotland, England, Italy, Netherlands, Norway, and Belgium.

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Article Synopsis
  • * Conducted at Alfred and Austin Hospitals in Melbourne, it examined 93 acute SCI cases to identify key predictors of clinically important pneumonia (CIP), finding 33 instances of CIP among the patients studied.
  • * The study identified four main predictors of increased pneumonia risk: male gender, motor complete injury, presence of chest trauma, and delayed intubation, paving the way for the development of a prediction tool for pneumonia in acute post-injury settings.
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Clinical trials evaluating early therapies after spinal cord injury (SCI) are challenging because of the absence of a rapid assessment. The aim of this study was to determine whether the severity and level of SCI could be established from a brief neurological assessment capable of being used in an emergency setting. A brief assessment called the SPinal Emergency Evaluation of Deficits (SPEED) was developed and retrospectively evaluated in a cohort of 118 patients with SCI.

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Study Design: A retrospective cohort study.

Objective: The aims of this study were to (1) determine the timing of surgery for traumatic thoracolumbar spinal cord injury (TLSCI) between 2010 and 2014 and (2) identify major delays in the process of care from accident scene to surgery.

Summary Of Background Data: Early spinal surgery may promote neurological recovery and reduce acute complications after TLSCI; however, it is difficult to achieve due to logistical issues and the frequent presence of other nonlife-threatening injuries.

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Early decompression may improve neurological outcome after spinal cord injury (SCI), but is often difficult to achieve because of logistical issues. The aims of this study were to 1) determine the time to decompression in cases of isolated cervical SCI in Australia and New Zealand and 2) determine where substantial delays occur as patients move from the accident scene to surgery. Data were extracted from medical records of patients aged 15-70 years with C3-T1 traumatic SCI between 2010 and 2013.

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