Purported Self-Organized Criticality of the Cardiovascular Function: Methodological Considerations for Zipf's Law Analysis.

Self-organized criticality is a universal theory for dynamical systems that has recently been applied to the cardiovascular system. Precise methodological approaches are essential for understanding the dynamics of cardiovascular self-organized criticality. This study examines how the duration and quality of data recording affect the analysis of cardiovascular self-organized criticality, with a focus on the beat-by-beat heart rate variability time series obtained from seven healthy subjects in a standing position.

Decision-Making in Patients with Vasovagal Syncope: A Preliminary Study.

The aim of this study was to evaluate the differences in performance during a decisional conflict task between subjects with emotional/blood phobia and those with an orthostatic vasovagal syncope. A total of 332 young subjects were included, from which 99 were excluded because of their condition or treatment. The subjects were classified into four groups depending on their responses to a questionnaire: 98 in a control group, 10 in an emotional/blood phobia syncope group, 38 in an orthostatic syncope group, and 87 in an unclear status group.

Autonomic Nervous System Influences on Cardiovascular Self-Organized Criticality.

Cardiovascular self-organized criticality has recently been demonstrated. We studied a model of autonomic nervous system changes to better characterize heart rate variability self-organized criticality. The model included short and long-term autonomic changes associated with body position and physical training, respectively.

Factors Influencing the Prognosis of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a long-term debilitating multisystem condition with poor prognosis. Studies that examined predictors of ME/CFS outcomes yielded contradictory results. We aimed to explore epidemiological and clinical prognostic factors of ME/CFS using operationalized criteria for recovery/improvement.

Zipf's Law of Vasovagal Heart Rate Variability Sequences.

Cardiovascular self-organized criticality (SOC) has recently been demonstrated by studying vasovagal sequences. These sequences combine bradycardia and a decrease in blood pressure. Observing enough of these sparse events is a barrier that prevents a better understanding of cardiovascular SOC.

Heart Rate Variability is Correlated with Perceived Physical Fitness in Elite Soccer Players.

Heart Rate Variability (HRV) has been typically used to monitor athletes' physical fitness readiness. The supine position maximizes parasympathetic tone, which is important for monitoring in continuous aerobic sports, however, this is not the case of team sports that rely on anaerobic intermittent bouts, thus increasing sympathetic activation and vagal withdrawal. We hypothesized that HRV during sympathetic activation and vagal withdrawal would be a useful marker to evaluate perceived physical fitness in team sports.

Altered Venous Function during Long-Duration Spaceflights.

Venous adaptation to microgravity, associated with cardiovascular deconditioning, may contribute to orthostatic intolerance following spaceflight. The aim of this study was to analyze the main parameters of venous hemodynamics with long-duration spaceflight. Venous plethysmography was performed on 24 cosmonauts before, during, and after spaceflights aboard the International Space Station.

Heart rate variability in the standing position reflects training adaptation in professional soccer players.

Purpose: To show that heart rate variability (HRV) in the standing position better reflects the way in which athletes adapt to training in so-called intermittent sports than the indicator of resting parasympathetic tone usually employed in endurance sports.

Methods: Twenty professional soccer players (intermittent sport) took part in a 5-week training session divided into three successive periods: "Warm-up", "Intensive training" and "Tapering". At the beginning and end of each of the three periods, a stand test was carried out and the heart rate was recorded, beat by beat (Polar Team 2).

Self-Organization of Blood Pressure Regulation: Clinical Evidence.

The pathogenesis of vasovagal syncope has remained elusive despite many efforts to identify an underlying dysfunction. Catastrophe theory explains the spontaneous occurrence of sudden events in some mathematically complex systems known as self-organized systems poised at criticality. These systems universally exhibit a power law initially described in earthquake occurrence: the Gutenberg Richter law.

Self-Organization of Blood Pressure Regulation: Experimental Evidence.

Blood pressure regulation is a prime example of homeostatic regulation. However, some characteristics of the cardiovascular system better match a non-linear self-organized system than a homeostatic one. To determine whether blood pressure regulation is self-organized, we repeated the seminal demonstration of self-organized control of movement, but applied it to the cardiovascular system.

Noisy fluctuation of heart rate indicates cardiovascular system instability.

Heart rate spontaneously fluctuates despite homeostatic regulatory mechanisms to stabilize it. Harmonic and fractal fluctuations have been described. Non-harmonic non-fractal fluctuation has not been studied because it is usually thought that it is caused by apparatus noise.

Moderate exercise effects on orthostatic intolerance while wearing protective clothing.

Introduction: Wearing protective clothing can have deleterious effects on operational capacities and can cause non-compensable thermal stress. We studied the effects of moderate exercise on orthostatic tolerance while wearing protective clothing in eight healthy subjects tolerant to orthostatism.

Methods: Subjects performed a 60-min moderate exercise on a treadmill followed by a 45-min head-up tilt test.

Skin vascular resistance in the standing position increases significantly after 7 days of dry immersion.

Actual and simulated microgravity induces hypovolemia and cardiovascular deconditioning, associated with vascular dysfunction. We hypothesized that vasoconstriction of skin microcirculatory bed should be altered following 7 days of simulated microgravity in order to maintain cardiovascular homeostasis during active standing. Eight healthy men were studied before and after 7 days of simulated microgravity modeled by dry immersion (DI).

Enforced physical inactivity increases endothelial microparticle levels in healthy volunteers.

A sedentary lifestyle has adverse effects on the cardiovascular system, including impaired endothelial functions. Subjecting healthy men to 7 days of dry immersion (DI) presented a unique opportunity to analyze the specific effects of enhanced inactivity on the endothelium. We investigated endothelial properties before, during, and after 7 days of DI involving eight subjects.

Heart rate variability in preterm infants and maternal smoking during pregnancy.

Objective: Tobacco smoke exposure increases the risk of premature birth and of dying of sudden infant death syndrome (SIDS). Prematurity significantly increases the risk of dying of SIDS, but mechanisms underlying this epidemiological finding are unclear. The cumulated effect of both prematurity and prenatal exposure to nicotine on autonomic heart rate control has not been studied.

WISE 2005: chronic bed rest impairs microcirculatory endothelium in women.

Sedentary behavior has deleterious effects on the cardiovascular system, including reduced endothelial functions. A 2-mo bed rest study in healthy women [women international space simulation for exploration (WISE) 2005 program] presented a unique opportunity to analyze the specific effects of prolonged inactivity without other vascular risk factors on the endothelium. We investigated endothelial properties before and after 56 days of bed rest in 8 subjects who performed no exercise (control group: No-EX) and in 8 subjects who regularly performed treadmill exercise in a lower body negative pressure chamber as well as resistance exercise (countermeasure group, EX).

Cardiovascular variables do not predict head-up tilt test outcome better than body composition.

Reflex syncope is a well-recognized phenomenon, but the understanding of its underlying pathophysiology remains limited. We hypothesized that patients with a history of syncope and a positive head-up tilt test (HUTT) outcome are in a "not-yet defined" abnormal state even before the head-up position. We performed a 45 min HUTT on 86 patients with a history of syncope.

Increased hydration alone does not improve orthostatic tolerance in patients with neurocardiogenic syncope.

In patients with neurocardiogenic syncope, the beneficial effects of increased daily fluid intake, without an accompanying high dose of salt, are unknown. Our aim was to (1) determine whether plasma volume was low in patients with recurrent neurocardiogenic syncope, and (2) determine how recommendation about increased daily fluid intake, without an accompanying high dose of sodium, effects plasma volume and if this potential therapy improves orthostatic tolerance. Eighty-six patients with neurocardiogenic syncope were recruited in a prospective randomized open study.

Early prediction of unexplained syncope by support vector machines.

The goal of the present study was to develop and evaluate a new method for the prediction of unexplained syncope occurrences. Diagnosis of syncope is currently based on the reproduction of symptoms in combination with hypotension and bradycardia induced by a 45 min 60-70 degrees head-upright tilt test (HUTT). The main drawback of this widely used test concerns its duration that reaches 55 min if the patient does not faint.