Objective: In March 2018, the Explorer study, an international, double-blind, randomised controlled trial (RCT), established that adding a TLC-NOSF (UrgoStart Contact, Laboratoires Urgo, France) dressing to good local standard of care (SoC) significantly and substantially increases wound closure and reduces the healing time of neuroischaemic diabetic foot ulcers (DFU). Besides the TLC-NOSF treatment, the wound duration was the only other covariate that had an influence on the wound closure rate in the regression model used in the original study. The purpose of this work was to further document the impact of wound duration on the healing outcomes of the DFUs included in the Explorer study and to discuss complementary pragmatic observations on the TLC-NOSF effect.
View Article and Find Full Text PDFLancet Diabetes Endocrinol
March 2018
Background: Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing.
View Article and Find Full Text PDFBackground: The global prevalence of type 2 diabetes is considerable. To avoid or delay its chronic complications, patients with type 2 diabetes should improve blood glucose management by adapting their life style. This involves changing the way in which diabetes is controlled.
View Article and Find Full Text PDFBackground: Health authorities recommend regular screening for the chronic complications of diabetes. The ENTRED survey results show that insufficient screening is undertaken. The DIABSAT program aims to improve care for diabetes patients in rural areas of the Midi-Pyrénées region, telemonitoring complications of diabetes through an itinerant screening service.
View Article and Find Full Text PDFIntroduction: Diabetic retinopathy (DR), diabetic kidney disease (DKD) and diabetic foot ulcer (DFU) represent a public health and economic concern that may be assessed with cost-of-illness (COI) studies.
Objectives: (1) To review COI studies published between 2000 and 2015, about DR, DKD and DFU; (2) to analyse methods used.
Methods: Disease definition, epidemiological approach, perspective, type of costs, activity data sources, cost valuation, sensitivity analysis, cost discounting and presentation of costs may be described in COI studies.
The Diabsat programme, coordinated by the Midi-Pyrénées diabetes network (Diamip), uses new technologies to enable patients to update the tests for chronic complications of their diabetes. In the long run, this favours their health prognosis and their quality of life.
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