Publications by authors named "Jacques Denis"

Background: In liaison psychiatry, issues related to multiple substance use disorders are encountered, but systematic assessment and treatment protocols are lacking. The implementation of psychoeducation groups with earlier access could be one solution, but it raises the question of how to systematically approach psychoeducation for multiple substance use disorders.

Subject And Method: Based on a narrative review of multiple substance use disorders in liaison psychiatry and the proposed treatments, we aimed to identify the possible systematisation of standardised psychoeducation.

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Background: Anorexia nervosa (AN) is reported to be on the rise. However, instances of fasting have been noted since antiquity. Can modern diagnoses be applied to circumstances very different from our own? Is there a continuum of symptoms whose meanings have evolved over centuries, or is AN a recent development?

Subjects And Methods: A literature review was conducted.

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Background: The general hospital can be regarded as a suitable place to provide secondary prevention for patients with alcohol misuse. It appears that screening and/or brief interventions on alcohol are acceptable for patients in hospital wards. The aim of this exploration study is to assess patients' expectations regarding the prevention of alcohol misuse carried out in general hospitals.

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Background: Alcohol use disorder is insufficiently treated because it is poorly detected. Improved screening in general hospitals is a major issue in treatment organisation.

Subject And Method: Through a retrospective exploratory study based on a review of medical records over four years (2016-19) before the COVID pandemic, we recorded the number of liaison psychiatric referrals for alcohol use disorder and identified two indicators: follow-up care implemented and survival at three years.

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Background: Since the outbreak of COVID-19, there has been an apparent increase in the utilization of mental health services and psychiatric disorders among youth. However, there is little data on youth mental health prior to the pandemic. Some authors suggest that the increase in the use of psychiatric care started before.

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Backround: Literature suggests that most people believe in free will and that this belief is associated with more prosocial behavior. However, with the advent of neuroscience, free will seems to have been progressively excluded from psychiatry. This paper is a narrative literature review of the ways in which mental health professionals' premises and beliefs in free will influence their clinical practice.

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Background: This article attempts to understand the difficulties encountered in the articulation of health care, particularly between the organic and psychiatric aspects. It also aims to provide solutions to these collaboration issues.

Methods: We realized a literature review based on articles dated from 2002 to 2021 and selected from following databases: Pubmed, Cochrane, Scopus, Cairn, Psychinfo and Google.

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Background: There is a lot of evidence for a bidirectional communication between the gut and brain. Dysbiosis and increase intestinal permeability may lead to a systemic low-grade inflammatory response or various neuroactive bacterial metabolite may cross gut barrier. Pro-inflammatory cytokines or bacterial metabolites such as short-chain fatty acid (SCFA) are known to pass through blood brain barrier and altered neurotransmitter metabolism or increase production of neurotoxic pathways.

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The Sarcoidosis Diagnostic Score (SDS) has been established to quantitate the clinical features consistent with sarcoidosis in a monocentric study. We aimed to confirm the diagnostic value of SDS in a large, multicontinental study and to assess the utility of SDS in differentiating sarcoidosis from alternative diagnoses, including infectious and noninfectious granulomatous diseases. We included patients with biopsy-confirmed sarcoidosis at nine centers across the world.

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Background: While many studies have investigated depression risk factors, few attempts have been made to weight, and compare them. Therefore, we conducted a prospective comparison of a sample of subjects suffering from major depressive disorder and a group of healthy subjects. We compared classic risk factors with internal elements such as personality, family dynamics and health locus of control.

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Background: Some behaviors or psychiatric conditions seem to be inherited from parents or explain by family environment. We hypothesized interactions between epigenetic processes, inflammatory response and gut microbiota with family surroundings or environmental characteristics.

Subjects And Methods: We searched in literature interactions between epigenetic processes and psychiatric disorders with a special interest for environmental factors such as traumatic or stress events, family relationships and also gut microbiota.

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Background: These last years adolescents in transition to young adulthood (ATYA) have become a new matter of research. This population encounter specific issues and challenges regarding their mental health particularly when they have attained age boundaries and deal with the issue of transition from child and adolescent mental health services (CAMHS) to adult mental health services (AMHS). Many key questions regarding how to sustain continuity of mental health care for ATYA during transition remain.

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Background: In Belgium, 82% of the population consumes alcohol occasionally while 10% consume in a way that can be seen as problematic. On a European level, only 8% of the people who can be characterized as having Alcohol Use Disorder (AUD) would have consulted professional assistance in the past year. In this context, the KCE (Belgian Health Care Knowledge Centre) has addressed multiple recommendations to health professionals to reduce the "treatment gap" concerning the patients' care: (1) encourage screening and preventative interventions, (2) promote the acquirement of communicational and relational competences (3) develop collaborations between professionals.

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Background: The multidisciplinary management of disabling chronic tinnitus in the audiophonology centre demonstrates its relevance. The detection and treatment of overlapping psychiatric pathologies is a crucial issue in the work of liaison psychiatry.

Subjects And Methods: A 10-year retrospective review of the activities of a university audiophonology centre with 166 patients who consulted for disabling chronic tinnitus and who underwent a Mini International Neuropsychiatric Interview.

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Background: Cannabinoid Hyperemesis Syndrome (CHS) is characterized by cyclic vomiting and compulsive need to take hot showers in the context of chronic cannabis use. Physicians' lack of knowledge of CHS often results in a diagnostic delay of several years. The purpose of this article is to describe CHS in order to enable physicians, and more particularly psychiatrists, to diagnose it as quickly as possible and thus avoid unnecessary additional invasive examinations.

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Background: Psychiatric disorders may be correlated with a low-grade systemic inflammation but the origin of this inflammatory response remains unclear and both genetics and environmental factors seems to be concerned. Recent researches observed that gut microbiota seems to have an impact on the brain and immune processes.

Method: We review recent literature to a better understanding of how microbiota interacts with brain, immunity and psychiatric disorders.

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Background & Aims: Sorafenib is the standard of care for advanced hepatocellular carcinoma (HCC). Combining sorafenib with another treatment, to improve overall survival (OS) within an acceptable safety profile, might be the next step forward in the management of patients with advanced HCC. We aimed to assess whether a combination of sorafenib and a statin improved survival in patients with HCC.

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Background: Among asylum seekers (AS), mental health conditions are highly prevalent. However this population group has poor access to adequate services and frequently incurs discontinuity of mental healthcare. Many factors explain discontinuity of mental healthcare for asylum seekers.

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Background: The links between psychiatry and immune dysfunctions are well known. By contrast, there are few studies that evaluate the link between neuroelectrophysiology and immune system disturbances.

Subjects And Methods: We retrospectively included 31 patients hospitalized between 2011 and 2012.

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Background: In previous studies we showed the interaction between depression and immunity. We observed that psychological stress seems to be important in this association. In this review we try to understand if psychological stress and immunity have similar or specific impact on the other psychiatric disorders.

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