Publications by authors named "Jacques Bodiguel"
Article Synopsis
- The study introduces a new type of pseudopeptide made with charged amino acids like lysine, aiming to explore how factors like chirality and backbone length affect these molecules' shape and behavior in solution.
- Results show that short and long peptide structures adopt a β-turn shape, with the longer chains exhibiting more variation due to side chains' flexibility and steric effects.
- Finally, using short lysine-containing aza-pseudopeptides in Pebax® 1074 membranes significantly enhances CO separation performance, especially with a specific pseudopeptidic dimer additive, improving selectivity and permeability.
Article Synopsis
- Molecular self-assembly plays a key role in creating organogels from low molecular weight compounds, which have gained popularity as new soft materials.
- The cyclic pseudopeptide cyclo-[-(d-Phe-azaPhe-Ala)-] exhibits the ability to self-assemble in aromatic solvents, forming organogels primarily through non-covalent forces like hydrogen bonding and π-stacking.
- Studies show its β-turn conformation in low concentrations and a balance between monomeric and supramolecular states at high concentrations, with findings indicating it can achieve high stiffness and effective recovery rates in phase selective gelation applications.
Di-tert-butyl 2-benzoyl-hydrazine-1,1-dicarboxyl-ate.
Acta Crystallogr Sect E Struct Rep Online
December 2007
The crystal structure of the title compound, C(17)H(24)N(2)O(5), was determined in the course of our studies on the preparation of two families of pseudopeptides, viz. hydrazino- and N-amino- peptides. The most significant inter-action in the crystal structure is a bifurcated inter-molecular N-H⋯O hydrogen bond.
View Article and Find Full Text PDFThere is an urgent need to understand the mechanism of activation of the frontline anti-tuberculosis drug isoniazid by the Mycobacterium tuberculosis catalase-peroxidase. To address this, a combination of NMR spectroscopic, biochemical, and computational methods have been used to obtain a model of the frontline anti-tuberculosis drug isoniazid bound to the active site of the class III peroxidase, horseradish peroxidase C. This information has been used in combination with the new crystal structure of the M.
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