Publications by authors named "Jacquemyn Y"

Objective: Non-communicable diseases (NCDs) increasingly contribute to maternal morbidity and mortality. We determined the association between NCDs and obstetric complications at Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda.

Methods: In this retrospective records review, we randomly selected records of women admitted for delivery at MRRH each month from January to December 2022, and extracted their socio-demographic and clinical histories.

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Article Synopsis
  • - Coarctation of the aorta (CoA) is a congenital heart defect found in 3-4 in every 10,000 births, often undiagnosed until adulthood, posing significant risks during pregnancy, including maternal and fetal complications.
  • - A case involved a 21-year-old pregnant woman with undiagnosed severe CoA, presenting with high blood pressure and a significant heart murmur, along with weak lower extremity pulses, indicating serious cardiovascular issues.
  • - After medical management, her condition required an endovascular procedure to place a stent at 23 weeks' gestation, which successfully improved blood flow and placental health, highlighting the need for careful monitoring and intervention in similar cases.
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Aims: To monitor fetal size and identify predictors for birthweight in women with gestational diabetes (GDM) and normal glucose tolerance (NGT).

Methods: Cohort study of 1843 women universally screened for GDM, with routine ultrasounds each trimester. Women with GDM and NGT were categorized in subgroups by birthweight centile.

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Aims: To determine the impact of breastfeeding on the risk of postpartum glucose intolerance in women with gestational diabetes.

Methods: Sub-analysis of two multi-centric prospective cohort studies (BEDIP-N and MELINDA) in 1008 women with gestational diabetes. Data were collected during pregnancy and at a mean of 12 weeks postpartum.

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  • Twin pregnancies face a high risk of extreme preterm birth (PTB) under 28 weeks, linked to serious health issues for newborns, and current treatments are limited.
  • A potential solution is the placement of a vaginal cerclage for women with a short cervix or cervical dilatation, aiming to reduce the chances of extreme PTB.
  • Two multicenter trials are planned in the Netherlands to evaluate the effectiveness of vaginal cerclage compared to standard care in these women, with specific recruitment goals and an analysis of costs and outcomes.
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Background: History has paid little attention to the childbirth of Marie Louise, second wife to the Emperor Napoleon I. Most historians state that the obstetrician Antoine Dubois needed to use his forceps during a difficult breech delivery. As practicing obstetricians we aimed to reconstruct the likely course of events using a forensic approach.

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Background: Postpartum weight retention (PPWR) has many health risks. Digital self-monitoring of weight can potentially make postpartum weight management easier. We aim to test to what extent the self-monitoring of weight, steps and mental health through an mHealth application increases postpartum weight loss and reduces the odds of substantial PPWR (≥5 kg).

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Key Clinical Message: Microbiological diagnosis of endometritis and appropriate antibiotic treatment based on the antibiogram is essential. We should remain critical about the potential etiologic pathogens, especially when traveling abroad and during pregnancy. Therefore, it is essential to obtain cultures prior to the administration of antibiotics.

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Background: Nontyphoidal serovars predominantly cause gastrointestinal infections. However, other clinical presentations, including urogenital infections, have been reported, although they are rather rare.

Case Presentation: This case is about a 33-year-old woman diagnosed with serovar Hvittingfoss ( Hvittingfoss) bacteremia and endometritis six days post uterine aspiration in the context of a missed abortion.

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Introduction: Maternal healthcare utilization, particularly the institutional delivery, is disproportionately low in rural Ethiopia. This study aimed to evaluate the effectiveness of an integrated package of community-based interventions on the improved knowledge of obstetric danger signs, birth preparedness, and institutional delivery services utilization in rural areas of Gamo zone, southern Ethiopia.

Methods: We conducted cluster-randomized controlled trial (NCT05385380) from 2019 to 2021 at the Arba Minch Health and Demographic Surveillance System site.

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  • Traditional cardiotocography (CTG) classifications often lead to inconsistent evaluations among different users, prompting the use of a fast-and-frugal tree (FFTree) flowchart to improve agreement in assessing fetal conditions.
  • This study compared interpretations of CTG traces using the FFTree method vs. FIGO classification by 8 experienced obstetricians, focusing on the suitability of STAN monitoring in fetuses likely experiencing hypoxic stress.
  • Results showed that FFTree classifications had a higher agreement rate for identifying fetuses unsuitable for STAN monitoring (60%) compared to FIGO (47%), highlighting the potential of FFTree to enhance diagnostic consistency in fetal surveillance.
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Background: In Belgium most women receive epidural analgesia during labour. Although, it offers satisfactory pain relief during labour, the risk on a series of adverse advents has been reported. The objective of this study was to determine factors associated with the intention of pregnant women, anticipating a vaginal birth, of requesting epidural analgesia during labour.

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Mental health problems and obesity are two common complications during pregnancy and postpartum. The preconception period is considered an appropriate period for prevention. Therefore, insights into interpregnancy mental health and the impact on weight and body composition are of interest to developing effective weight management strategies.

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  • The INTER-ACT postpartum lifestyle intervention was evaluated to see its impact on depression, anxiety, sense of coherence, and quality of life in women during the first year after childbirth, involving 1,047 participants split into intervention and control groups.
  • Results indicated no significant difference in anxiety or quality of life, but women who participated in the intervention experienced improved depression symptoms and sense of coherence, with varying effects based on pre-pregnancy BMI.
  • Specifically, women with normal/overweight BMI showed a greater decrease in depression symptoms compared to the control group, while those with pre-pregnancy obesity had less severe increases in depression in the intervention group.
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  • The study investigates the pregnancy outcomes of normal glucose tolerant (NGT) women with low glycemic levels during an oral glucose tolerance test (OGTT), focusing on various glycemia ranges.
  • Researchers from Belgium analyzed data from 1,841 pregnant women to compare NGT women with low glycemia (<3.9 mmol/L) to those with higher levels, adjusting for factors like body mass index (BMI) and weight gain.
  • Results show that women with glycemia below 3.9 mmol/L had better metabolic health but a significantly higher risk of having a baby with a birth weight under 2.5 kg, highlighting potential concerns for this group.
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Objective: The aim of our study is to systematically review the literature about available devices facilitating perineal support during defecation in patients with obstructive defecation syndrome (ODS) and posterior pelvic organ prolapse (POP).

Methods: We searched for the terms "defecat/ion or ODS" and" pessar/ies or device/aid/tool/perineal/perianal/prolapse and support" in MEDLINE, PubMed and Web of Science. Data abstraction was performed according to PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analysis) guidelines.

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Introduction And Hypothesis: Of women with symptomatic prolapse, 13-39% experience voiding dysfunction (VD). The aim of our observational cohort study was to determine the effect of prolapse surgery on voiding function.

Methods: Retrospective analysis of 392 women who underwent surgery between May 2005 and August 2020.

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Purpose: This study aims to describe the differences in the urethral motion profile (UMP) of primiparous and multiparous women immediately postpartum.

Methods: This prospective study recruited 65 women (29 primiparous, 36 multiparous) one-seven days postpartum. The patients underwent a standardised interview and two-dimensional translabial ultrasound (TLUS).

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Background: Despite efforts to make maternal health care services available in rural Ethiopia, utilisation status remains low. Therefore, this study aimed to assess maternal health care services' status and determinants in rural Ethiopia.

Methods: The study used quasi-experimental pre- and post-comparison baseline data.

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Introduction: Human pregnancy is considered term from 37+0/7 to 41+6/7 weeks. Within this range, both maternal, fetal and neonatal risks may vary considerably. This study investigates how gestational age per week is related to the components of perinatal mortality and parameters of adverse neonatal and maternal outcome at term.

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Context: More data are needed on the potential benefits and risks of gestational weight gain (GWG) less than recommended and excessive GWG in women with gestational diabetes (GDM) compared to women with normal glucose tolerance (NGT) during pregnancy.

Objective: This work aimed to evaluate association of gestational weight gain (GWG) as low, within, or above (excessive) according to Institute of Medicine (IOM) guidelines, with pregnancy outcomes in women with gestational diabetes (GDM) and normal glucose tolerance (NGT).

Methods: This prospective cohort study included 7 Belgian hospitals and 1843 women receiving universal GDM screening with a 75-g oral glucose tolerance test.

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Objective: To study the evolution of maternal mental health during the first year after childbirth in women with previous excessive gestational weight gain, and the relationship with postpartum weight retention and body composition.

Methods: Anthropometric and mental health data of 505 women of the INTER-ACT RCT control group were collected and assessed using descriptive statistics and mixed model analyses.

Results: At 6 weeks postpartum 28% of women reported depressive symptoms, 46% anxiety, 47% low sense of coherence and 48% low quality of life.

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Aims: To characterize women with gestational diabetes mellitus (GDM) positive for type 1 diabetes-related autoimmune antibodies (T1D-related autoantibodies) in pregnancy and to evaluate their risk for long-term glucose intolerance.

Methods: In a multi-centric prospective cohort study with 1843 women receiving universal screening for GDM with a 75 g oral glucose tolerance test (OGTT), autoantibodies were measured in women with GDM: insulin autoantibodies (IAA), islet cell antibodies (ICA), insulinoma-associated protein-2 antibodies (IA-2A) and glutamic acid decarboxylase antibodies (GADA). Long-term follow-up ( ± 4.

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Aim: To determine the association between thyroid function and the risk of developing gestational diabetes mellitus (GDM) and adverse pregnancy outcomes. Methods: This case−control study was a sub-analysis of the BEDIP-N study, in which 199 GDM women were matched for age and body mass index with 398 controls. Thyroid-stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3), and thyroid peroxidase (TPO) antibodies were measured at 6−14 weeks and 26−28 weeks during pregnancy.

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