Publications by authors named "Jacqueline Yap"
Article Synopsis
- Epigenetic mechanisms involve complex interactions between transcriptional activity, chromatin accessibility, and DNA methylation during neural progenitor cell differentiation.
- Researchers found that many enhancers experience rapid changes in accessibility linked to different transcription factor expression periods, highlighting a dynamic regulatory landscape.
- Interestingly, DNA methylation changes occur later and in a unidirectional manner, suggesting that chromatin dynamics precede and influence the timing of DNA demethylation and enhancer regulation.
A randomized controlled trial of auricular transcutaneous electrical nerve stimulation for managing posthysterectomy pain.
Evid Based Complement Alternat Med
July 2011
Background. A patient- and assessor-blinded randomized controlled trial was conducted to examine the effectiveness of auricular transcutaneous electrical nerve stimulation (TENS) in relieving posthysterectomy pain. Method.
View Article and Find Full Text PDFUnlabelled: Acceptance of chronic pain has become an important concept in understanding and predicting that chronic pain sufferers can remain engaged with meaningful aspects of life. Assessment of acceptance has been facilitated by the development of Chronic Pain Acceptance Questionnaire (CPAQ). In this study, we aimed to test the reliability and validity of translated Chinese version of CPAQ to use this important tool in the future management of Hong Kong Chinese patients with chronic nonmalignant pain.
View Article and Find Full Text PDFObjective: This study was conducted to examine the psychometric properties of a Chinese translation of the Pain Catastrophizing Scale (HK-PCS).
Design/patients: Patients aged 18-79 years (N = 130) with chronic nonmalignant pain attending an outpatient multidisciplinary pain center in Hong Kong participated in this cross-sectional study.
Method: Subjects completed a set of health-related instruments: HK-PCS, Hospital Anxiety and Depression Scale, Roland Morris Disability Questionnaire, SF-36 Health Survey, and a general demographic questionnaire.
Objective: To evaluate attitudes of Chinese patients towards day-case surgery.
Design: Prospective cross-sectional questionnaire survey.
Setting: District public hospital, Hong Kong.