Silicon-Based Glucose Oxidase Working Electrode for Glucose Sensing.

We created a glucose oxidase (GOx) working electrode on a silicon-on-insulator (SOI) wafer for glucose sensing. The SOI wafer was electrically connected to a copper wire, and the GOx was immobilized onto the hydrophilized SOI surface via silanization with aminopropyltriethoxysilane and glutaraldehyde. Electrochemical analysis (i.

Kaempferol inhibits Entamoeba histolytica growth by altering cytoskeletal functions.

The flavonoid kaempferol obtained from Helianthemum glomeratum, an endemic Mexican medicinal herb used to treat gastrointestinal disorders, has been shown to inhibit growth of Entamoeba histolytica trophozoites in vitro; however, the mechanisms associated with this activity have not been documented. Several works reported that kaempferol affects cytoskeleton in mammalian cells. In order to gain insights into the action mechanisms involved in the anti-amoebic effect of kaempferol, here we evaluated the effect of this compound on the pathogenic events driven by the cytoskeleton during E.

The flavonoid (-)-epicatechin affects cytoskeleton proteins and functions in Entamoeba histolytica.

Unlabelled: Human amoebiasis is an intestinal disease with a global distribution. Due to reports of parasite resistance or susceptibility reduction to metronidazole treatment, there is a renewed interest for the search of new molecules with antiamoebic activity. The flavonoid (-)-epicatechin that was isolated from the Mexican medicinal plant Geranium mexicanum HBK has an in vitro activity against E.

Ultrastructural changes on Entamoeba histolytica HM1-IMSS caused by the flavan-3-ol, (-)-epicatechin.

The flavan-3-ol, (-)-epicatechin has been previously identified as the most important antiamoebic compound among the extracts from two medicinal plants: Rubus coriifolius and Geranium mexicanum. Here we report the effects of epicatechin on Entamoeba histolytica morphology, analyzed by electronic microscopy. E.