Alcohol use is associated with affective and interoceptive network alterations in bipolar disorder.

Introduction: Alcohol use in bipolar disorder (BD) is associated with mood lability and negative illness trajectory, while also impacting functional networks related to emotion, cognition, and introspection. The adverse impact of alcohol use in BD may be explained by its additive effects on these networks, thereby contributing to a poorer clinical outcome.

Methods: Forty BD-I (DSM-IV-TR) and 46 psychiatrically healthy controls underwent T1 and resting state functional MRI scanning and the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) to assess alcohol use.

Rhyme and Word Placement in Storybooks Support High-Level Verb Mapping in 3- to 5-Year-Olds.

High-level verbs can be especially challenging for young children to initially map to meaning. This study manipulated the format of a storybook designed to support such verb learning from shared reading. We tested whether 3- to 5-year-olds ( = 38) could remember the referents of eight new verbs when presented as essential actions within a narrative story but with differences in placement.