Cardiac status in well-treated patients with thalassemia major.

Objective: To assess cardiac status in a large group of patients with thalassemia major who had been treated in a standard way since their early infancy with intensive transfusions and deferoxamine chelation therapy and who had good compliance with this regimen.

Methods And Results: We assessed clinically and echocardiographically 202 thalassemia major patients aged 27.3 +/- 6.