Impact of Glucose-Lowering Medications on Health-Related Quality of Life in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).

Objective: Diabetes is associated with reduced health-related quality of life (HRQoL). Information on the relationship between HRQoL and glucose-lowering medications in recently diagnosed type 2 diabetes (T2D) is limited. We assessed changes in HRQoL in participants with T2D receiving metformin plus one of four glucose-lowering medications in Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).

Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight.

Objective: We evaluated the effect of optimizing metformin dosing on glycemia and body weight in type 2 diabetes.

Research Design And Methods: This was a prespecified analysis of 6,823 participants in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) taking metformin as the sole glucose-lowering drug who completed a 4- to 14-week (mean ± SD 7.9 ± 2.

Exploring daily affective changes in university students with a mindful positive reappraisal intervention: A daily diary randomized controlled trial.

Brief and cost-effective interventions focused on emotion regulation techniques can buffer against stress and foster positive functioning. Mindfulness and positive reappraisal are two techniques that can mutually enhance one another to promote well-being. However, research testing the effectiveness of interventions combining mindfulness and reappraisal is lacking.

Music therapy to reduce agitation in dementia.

Background: Music therapy is a non-pharmacological intervention that aims to increase emotional wellbeing through cognitive stimulation and social interaction.

Aim And Method: I aimed to investigate the efficacy of group music therapy to reduce agitation in people with dementia. To this end, I carried out a systematic review of the literature.

Changes in renal function following Roux-en-Y gastric bypass: a prospective study.

Background: Studies of the impact of Roux-en-Y gastric bypass (RYGB) on renal function have shown mixed results. We constructed this prospective repeated-measures controlled study to characterize this response and identify the best method of gauging renal function in this setting.

Methods: Clinical data, serum creatinine (SC), and 24-h urine were collected 1 week before and 6 months following RYGB.

Urolithiasis risk factors in the bariatric population undergoing gastric bypass surgery.

Background: Previous studies have suggested an increased risk of forming symptomatic urolithiasis after Roux-en-Y gastric bypass (RYGB) attributed to the development of hyperoxaluria. The objective of our investigation was to evaluate changes in the urine milieu after RYGB that might explain the increased risk of urolithiasis.

Methods: Patients underwent serum and urine chemistry tests 1 week before and 6 months after RYGB at a university hospital.