Publications by authors named "Jacqueline Antoun"

Article Synopsis
  • Annual albuminuria screening is crucial for early nephropathy detection in diabetes patients, with guidelines recommending annual tests for type 2 diabetes and for those with type 1 after 5 years.
  • At the Eskind Diabetes Clinic, testing rates were low due to the absence of a structured approach, prompting quality improvement interventions involving electronic health record dashboards and daily staff reminders.
  • Following these interventions, annual testing rates significantly increased from 69% to 82% in six months, suggesting that similar strategies could enhance testing rates in other clinics and improve overall patient outcomes.
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Pseudohypoparathyroidism (PHP) is a rare hormone resistance syndrome caused by mutations in . This cross-sectional study investigated whether PHP patients with parathyroid hormone (PTH), thyrotropin (thyroid stimulating hormone; TSH), and free thyroxine (T4) levels at goal required higher doses of levothyroxine and calcitriol than recommended by current guidelines to overcome mineral ion abnormalities due to hormone resistance. Baseline demographic and clinical data of participants enrolled in PHP research studies between 2012-2021 were collected via retrospective chart review.

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Changes in macrophage phenotype in injured muscle profoundly influence regeneration. In particular, the shift of macrophages from a proinflammatory (M1 biased) phenotype to a proregenerative (M2 biased) phenotype characterized by expression of CD206 and CD163 is essential for normal repair. According to the current canonical mechanism regulating for M1/M2 phenotype transition, signaling through PPARδ is necessary for obtaining the M2-biased phenotype.

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