Publications by authors named "Jacopo Pinto"
Stem Cell Reports
October 2024
Article Synopsis
- - Adult neural stem cells (NSCs) were traditionally believed to be rare and mostly found in specific brain regions, but new findings suggest that parenchymal astrocytes (ASs) also play a role in neurogenesis, especially after brain injuries.
- - A study reconstructed the activation patterns of STR ASs following an excitotoxic lesion in mice, revealing that ASs have widespread neurogenic potential, primarily activated near the injury site alongside various reactive AS subtypes.
- - The research showed that, like in established NSC niches, local ASs undergo regular activation and quickly revert to a quiescent state, with their offspring expanding briefly, which implies that STR ASs have a comparable capacity for neural stem cell activity
