Adaptive optics scanning laser ophthalmoscopy and optical coherence tomography (AO-SLO-OCT) system for mouse retina imaging.

Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) are imaging technologies invented in the 1980s that have revolutionized the field of retinal diagnostics and are now commonly used in ophthalmology clinics as well as in vision science research. Adaptive optics (AO) technology enables high-fidelity correction of ocular aberrations, resulting in improved resolution and sensitivity for both SLO and OCT systems. The potential of gathering multi-modal cellular-resolution information in a single instrument is of great interest to the ophthalmic imaging community.

Efficient implementation of the Shack-Hartmann centroid extraction for edge computing.

Adaptive optics (AO) is an established technique to measure and compensate for optical aberrations. One of its key components is the wavefront sensor (WFS), which is typically a Shack-Hartmann sensor (SH) capturing an image related to the aberrated wavefront. We propose an efficient implementation of the SH-WFS centroid extraction algorithm, tailored for edge computing.

Adaptive optics in the mouse eye: wavefront sensing based vs. image-guided aberration correction.

Adaptive Optics (AO) is required to achieve diffraction limited resolution in many real-life imaging applications in biology and medicine. AO is essential to guarantee high fidelity visualization of cellular structures for retinal imaging by correcting ocular aberrations. Aberration correction for mouse retinal imaging by direct wavefront measurement has been demonstrated with great success.

Improvement of coupling efficiency in free-space optical communication with a multi-actuator adaptive lens.

In free-space optical communication, the propagation of a laser beam through the atmosphere causes wavefront distortions that decrease the coupling efficiency (CE) from free space to single-mode fiber. This tremendously degrades the performance of the communication channel even in the case of weak turbulence regime. In this Letter, we demonstrate that a multi-actuator adaptive lens working in closed loop with a wavefront sensor can strongly reduce the effect of turbulence while reducing the system complexity with respect to correction systems using deformable mirrors or liquid crystal spatial light modulators.

Fast stabilization of a high-energy ultrafast OPA with adaptive lenses.

The use of fast closed-loop adaptive optics has improved the performance of optical systems since its first application. Here we demonstrate the amplitude and carrier-envelope phase stabilization of a high energy IR optical parametric amplifier devoted to Attosecond Science exploiting two high speed adaptive optical systems for the correction of static and dynamic instabilities. The exploitation of multi actuator adaptive lenses allowed for a minimal impact on the optical setup.

Effect of a contact lens on mouse retinal in vivo imaging: Effective focal length changes and monochromatic aberrations.

For in vivo mouse retinal imaging, especially with Adaptive Optics instruments, application of a contact lens is desirable, as it allows maintenance of cornea hydration and helps to prevent cataract formation during lengthy imaging sessions. However, since the refractive elements of the eye (cornea and lens) serve as the objective for most in vivo retinal imaging systems, the use of a contact lens, even with 0 Dpt. refractive power, can alter the system's optical properties.

Real-time adaptive optics testbed to investigate point-ahead angle in pre-compensation of Earth-to-GEO optical communication.

We explore adaptive optics (AO) pre-compensation for optical communication between Earth and geostationary (GEO) satellites in a laboratory experiment. Thus, we built a rapid control prototyping breadboard with an adjustable point-ahead angle where downlink and uplink can operate both at 1064 nm and 1550 nm wavelength. With our real-time system, beam wander resulting from artificial turbulence was reduced such that the beam hits the satellite at least 66% of the time as compared to merely 3% without correction.