Background: Treatment strategies for cutaneous squamous cell carcinoma in situ (cSCCIS) are many but reported cure rates are variable and few studies report 5-year follow-up data.
Objective: To evaluate the treatment of cSCCIS by curettage followed by topical imiquimod 5% cream (C&I).
Methods: We evaluated all immunocompetent patients with biopsy proven cSCCIS treated by C&I between January 2008 and December 2012.