Haloperidol for the Treatment of Delirium in ICU Patients.

Background: Haloperidol is frequently used to treat delirium in patients in the intensive care unit (ICU), but evidence of its effect is limited.

Methods: In this multicenter, blinded, placebo-controlled trial, we randomly assigned adult patients with delirium who had been admitted to the ICU for an acute condition to receive intravenous haloperidol (2.5 mg 3 times daily plus 2.

Restriction of Intravenous Fluid in ICU Patients with Septic Shock.

Background: Intravenous fluids are recommended for the treatment of patients who are in septic shock, but higher fluid volumes have been associated with harm in patients who are in the intensive care unit (ICU).

Methods: In this international, randomized trial, we assigned patients with septic shock in the ICU who had received at least 1 liter of intravenous fluid to receive restricted intravenous fluid or standard intravenous fluid therapy; patients were included if the onset of shock had been within 12 hours before screening. The primary outcome was death from any cause within 90 days after randomization.

Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU.

Background: Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear.

Methods: In this European, multicenter, parallel-group, blinded trial, we randomly assigned adults who had been admitted to the ICU for an acute condition (i.e.

[Audience response-systems enhance the learning environment].

The purpose of this article was to describe the possibilities gained by using an electronic voting system (EVS), the existing evidence to determine whether an EVS affects learning proceeds, challenges in EVS and perspectives for EVS in Danish medical training. Audience Response-Systems (ARS) seem suited to enhance participants' activity and attention. The technology as such holds the potential to enhance learning outcome, but changes in the pedagogical method are needed.

Good experiences with an audience response system used in medical education.

Introduction: Audience response systems (ARS) are increasingly being used to heighten participants' involvement. Knowledge of technical and pedagogical challenges is, however, limited. The purpose of this paper is to evaluate ARS as a tool for 1) evaluation, 2) knowledge testing, 3) attention raising and 4) discussion stimulation.

[Glasgow Coma Scale < 9 as a criterion for tracheal intubation of patients with traumatic brain injuries?].

Guidelines use GCS < 9 as a criterion for tracheal intubation of patients with traumatic brain injuries. Our hypothesis was that there was actually no evidence for using this criterion. We searched relevant databases and found no association between a particular GCS and impaired pharyngeal control, but we did find an association between a low GCS and respiratory insufficiency.