Publications by authors named "Jacob Scadden"
Molecular motors are found in many living organisms. One such molecular machine, the ion-powered rotary motor (IRM), requires the movement of ions across a membrane against a concentration gradient to drive rotational movement. The bacterial flagellar motor (BFM) is an example of an IRM which relies on ion movement through the stator proteins to generate the rotation of the flagella.
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- The study highlights the detection of SARS-CoV-2 in stool samples, indicating potential for faecal-oral transmission and the need for reliable testing methods.
- Researchers developed a sensitive and effective method utilizing real-time RT-qPCR to detect low levels of the virus in stool samples, achieving detection as low as 1 viral particle per mg.
- The findings aim to improve the understanding of SARS-CoV-2 presence in the gut and ensure the safety of microbiome-based procedures like faecal microbiota transplants (FMT).
BK virus (BKV) is a polyomavirus that is able to cause renal dysfunction in transplanted grafts BK virus-associated nephritis (BKVAN). This condition was mis-diagnosed in the past due to clinical and histopthological similarities with acute rejection. Due to the prevalence of the virus in the population, it is an important pathogen in this context, and so it is important to understand how this virus functions and its' relationship with the pathogenesis of BKVN.
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