Eight Weeks of Daily Cannabidiol Supplementation Improves Sleep Quality and Immune Cell Cytotoxicity.

Background: The endocannabinoid system is active in nervous and immune cells and involves the expression of two cannabinoid receptor genes (CB1 and CB2), along with endogenous endocannabinoid ligands, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (anandamide), and their synthetic enzymes. Cannabidiol (CBD) is a non-intoxicating exogenous cannabinoid agonist derived from plants that, at high doses, has received FDA approval as an anticonvulsant for epileptic seizures, and at low doses is marketed as a food-grade supplement for improved mental health, sleep quality, and immunological function. At present, the predominance of published CBD clinical research has focused on ameliorative or disease-specific intervention, with few trials investigating CBD effects in healthy populations.

Effects of Oral Cannabidiol on Health and Fitness in Healthy Adults: An 8-Week Randomized Trial.

Background: There is a lack of research on the effects of cannabidiol (CBD) on health-related fitness, physical activity, cognitive health, psychological wellbeing, and concentrations of C-reactive protein (CRP) in healthy individuals. CBD has potential anti-inflammatory and neuroprotective effects.

Methods: This study aimed to investigate the effects of 8 weeks of CBD on the above-mentioned measures in healthy individuals.

Chronic cannabis use is associated with altered monocyte phenotype, immune response, and depression in physically active individuals.

This study evaluated depression, monocyte phenotype, and immune function in physically active cannabis users. Participants ( = 23) were classified as either cannabis users (CU,  = 11) or non-users (NU,  = 12). White blood cells isolated from blood were analyzed for co-expression of cluster of differentiation 14 and 16 using flow cytometry.

Regular Use of Cannabis in Female Athletes Is Associated With a Reduction in Early Anaerobic Power Production.

Lisano, JK, Flores, VA, Kisiolek, JN, and Stewart, LK. Regular use of cannabis in female athletes is associated with a reduction in early anaerobic power production. J Strength Cond Res 37(3): 616-622, 2023-Despite a growing number of claims related to the ability of cannabis use to affect health and performance, there is limited research available, especially in female athletes.

Relationship between training load and recovery in collegiate American football players during pre-season training.

: The purpose of this study was to examine the relationship between training load and next-day recovery in collegiate American football (AF) players during pre-season.: Seventeen athletes (Linemen, n = 6; Non-linemen, n = 11) participated in the 14-day study wearing monitoring (accelerometer + heart rate) sensors during on-field practice sessions throughout pre-season to assess the physiological (PL), mechanical load (ML) and recording of session RPE (sRPE load) immediately post-practice. Prior to practice, participants completed a drop-jump reactive strength index (RSI) test and reported perceived recovery status (PRS).

Sleep Duration Correlates With Performance in Ultra-Endurance Triathlon.

The relationship between sleep duration, sleep quality, and race completion time during each stage of a 3-day ultra-endurance triathlon (stage 1: 10-km swim, 146-km cycle; stage 2: 276-km cycle; and stage 3: 84.4-km run) was investigated. Seventeen triathletes partook in sleep analysis throughout the ultra-endurance multiday triathlon using an actigraphy wristband.

Kefir Is a Viable Exercise Recovery Beverage for Cancer Survivors Enrolled in a Structured Exercise Program.

Purpose: This study investigated the effects of 12 wk of postexercise kefir consumption in cancer survivors who have undergone chemotherapy and/or radiation therapy.

Methods: All participants were enrolled in a structured exercise training program and separated into kefir (KEF) or control (CON) treatment groups. KEF consumed 8 oz.

Short Term, Oral Supplementation with Optimized Curcumin Does Not Impair Performance Improvements Associated with High Intensity Interval Training.

Curcumin may improve athletic performance through a reduction in inflammation following exercise and improve mental states of well-being. The purpose of this investigation was to explore the effects of a 14 day HIIT intervention and oral supplementation with Longvida optimized curcumin on athletic performance, lactate response, and well-being. Sixteen males and twenty females participated in a double-blinded, randomized, placebo-controlled trial to explore the effects of Longvida(R) optimized curcumin (1.

Ultra-endurance triathlon performance and markers of whole-body and gut-specific inflammation.

Purpose: To examine the influence of the Ultraman Florida triathlon (3 days of non-continuous racing; stage 1: 10 km swim and 144.8 km cycle; stage 2: 275.4 km cycle; stage 3: 84.

Chronic cannabis use and circulating biomarkers of neural health, stress, and inflammation in physically active individuals.

Previous research has associated cannabis use with altered circulating neurotrophins and biomarkers of immune health, but these relationships have yet to be fully explored in physically active individuals. The specific aim of this study was to explore the relationships between biomarkers of neural health: nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), immune health: interleukin 6 (IL-6), C-reactive protein (CRP), and cortisol, as well as the presence of depression, in physically active cannabis users (CU) and nonusers (NU). Male and female participants ( = 30; CU, = 15, NU, = 15) provided intravenous blood samples and underwent assessment of body composition, maximal oxygen consumption, and depression (Beck Depression Inventory-II (BDI-II)).

The effect of cold ambient temperature and preceding active warm-up on lactate kinetics in female cyclists and triathletes.

The aim of this study was to evaluate the effect of cold ambient temperature on lactate kinetics with and without a preceding warm-up in female cyclists/triathletes. Seven female cyclists/triathletes participated in this study. The randomized, crossover study included 3 experimental visits that comprised the following conditions: () thermoneutral temperature (20 °C; NEU); () cold temperature (0 °C) with no active warm-up (CNWU); and () cold temperature (0 °C) with 25-min active warm-up (CWU).

Adipose Lipolysis Unchanged by Preexercise Carbohydrate Regardless of Glycemic Index.

Purpose: This study aimed to determine the effect of preexercise carbohydrate of different glycemic indices on subcutaneous abdominal adipose tissue (SCAAT) metabolism and running performance.

Methods: Ten trained male runners completed three experimental trials consisting of 30 min at 60% maximal oxygen consumption, 30 min at 75% maximal oxygen consumption, and a 5-km time trial. Thirty minutes before exercise, participants consumed one of three beverages: 1) 75 g low glycemic index modified starch supplement (UCAN), 2) 75 g high glycemic index glucose-based supplement (G), or 3) a flavor-matched noncaloric placebo (PL).

Accuracy of Resting Metabolic Rate Prediction Equations in Athletes.

Jagim, AR, Camic, CL, Kisiolek, J, Luedke, J, Erickson, J, Jones, MT, and Oliver, JM. Accuracy of resting metabolic rate prediction equations in athletes. J Strength Cond Res 32(7): 1875-1881, 2018-The purpose of this study was to determine the accuracy of 5 different resting metabolic rate (RMR) prediction equations in male and female athletes.