Pre-existing atrial fibrillation and risk of arterial thromboembolism and death in intensive care unit patients: a population-based cohort study.

Introduction: Pre-existing atrial fibrillation (AF) may worsen prognosis in patients admitted to the intensive care unit (ICU).

Methods: In a cohort study (2005-2011) including all patients with first-time ICU admissions in Denmark (n=57,110), we compared patients with and without pre-existing AF and estimated absolute risks and relative risks (RRs) of arterial thromboembolism and death within 30 days and 365 days following admission, using Kaplan-Meier methods and multivariate regression analyses. We analysed the prognostic impact of AF within strata of patient age, sex, coexisting cardiac diseases, and ICU therapies.

Pre-existing atrial fibrillation and risk of arterial thromboembolism and death following pneumonia: a population-based cohort study.

Objectives: To examine the effect of pre-existing atrial fibrillation (AF) and associated therapy on the risk of arterial thromboembolism (ATE) and death following pneumonia.

Design, Setting And Participants: Population-based cohort study (1997-2012) of 88,315 patients with first-time hospitalisation with pneumonia in Northern Denmark.

Results: Of the included patients (median age 73.

[Metformin treatment causes persisting lactic acidosis after cardiac arrest].

Metformin associated lactic acidosis (MALA) is a rare condition with a prevalence of 3 per 100,000 patient-years. The reported mortality is about 50%. We describe a case of MALA in a 61-year-old obese, type II diabetic male who suffered a sudden cardiac arrest.