Publications by authors named "Jacob G"

This study aimed to assess the immediate effects of transcutaneous spinal direct current stimulation (tsDCS) on pain outcomes, measured using the visual analog scale (VAS) and pressure pain thresholds in a cohort of 55 participants experiencing chronic pain using a controlled, randomized trial with 55 participants allocated into 2 groups: 2 mA and 0.5 mA of tsDCS for 20 min. Anodal stimulation was applied on the 12th thoracic vertebra, with the cathode positioned on the 7th cervical vertebra.

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Background: Goldenhar syndrome is a clinically heterogeneous disorder defined by a rare combination of congenital anomalies-an eye abnormality, in addition to two of the following three: ear anomalies, mandibular malformations, and vertebral defects. Notably, children with Goldenhar syndrome present with a high incidence of cervical spine malformations.

Clinical Case: In this report, we present an unusual case of a 15-year-old child with Goldenhar syndrome, who additionally presents with some clinical features of VACTERL syndrome.

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Many adults suffer from insomnia. Cognitive-behavioural therapy for insomnia is the recommended treatment option, but access to it is not readily available. Digital interventions have the potential to close the treatment gap by offering scalable and cost-efficient options.

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Article Synopsis
  • Psychiatric patients have a shorter life expectancy than the general population, partly due to medical, behavioral, and social factors, with venous thromboembolism (VTE) being a significant concern.
  • VTE occurs more frequently in psychiatric patients—around 2 to 3 times higher than in the general population—due to factors like metabolic issues, medications, and genetic predispositions.
  • Addressing the elevated risk of VTE through better risk assessment and preventive measures is crucial to improving health outcomes for these individuals.
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The aim was to evaluate the chemical, morphological aspects and microhardness of root dentin after treatment with Triton™ solution. Twenty blocks of root dentin were distributed in two groups (n = 10): Control (C) (2.5% NaOCl+17% EDTA+2.

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Background: Physiotherapy is effective to reduce pain and improve the quality of life of people living with chronic pain. To offer high-quality physiotherapy services, these services must be patient-centred and respond to patients' needs. However, few studies seem to target patients' perceived needs, whereas more studies tend to focus on needs assessed by healthcare experts, which are not always in line with patients' perceived needs.

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Objectives: A "patient-researcher" training intervention was designed to improve participants' empowerment by building on their level of critical health literacy and to build a trustful partnership between participants and researchers, with the longer-term objective of co-constructing a community-based research project. The participants in the training intervention were recruited through the collaborative research platform "Seintinelles". This training intervention was aimed at patients or former patients suffering from cancer.

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Background: Prenatal care provides pregnant women with repeated opportunities for prevention, screening and diagnosis that have no current extension to future fathers. It also contributes to women's general better access to health. The goal of PARTAGE study was to evaluate the level and determinants of adherence to a prenatal prevention consultation dedicated to men.

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Neuromarketing is the application of neuroscience and cognitive science to understand and influence consumer behavior and the different underlying decision-making processes. This neuromarketing bibliometric study uses Scopus for bibliographic data and Biblioshiny and Citespace for the overall analysis. Annual scientific production is considered to outline some general lines of critical trends in volume over time.

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Persons with complex care needs that arise due to chronic health conditions, serious illness, or social vulnerability are at increased risk of adverse health outcomes during transitions in care. To inform the development of a best practice guideline, a systematic review was conducted to examine the effect that navigation support has during transitions in care on quality of life, emergency department visits, follow-up visits, patient satisfaction, and readmission rates for persons with complex care needs. Eight databases were searched from 2016 to 2023.

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Background: Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease with diverse symptomatology, significantly impacting patients' quality of life (QoL). While pharmacological therapies focus primarily on reducing inflammation and relapse rates, non-pharmacological interventions, including digital health applications, have shown promise in improving QoL among persons with MS (PwMS). Pilot studies had shown the feasibility and acceptability of levidex, a digital health application based on cognitive behavioral therapy (CBT) principles, a broad set of behavior change techniques, and relevant lifestyle-change advice.

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Health tourism, encompassing both wellness and medical tourism, serves individuals seeking preventive care, relaxation, and medical treatments in diverse global destinations. This bibliometric study leverages Scopus for bibliographic data to analyze the scientific production in health tourism. The analysis, conducted using Biblioshiny and CiteSpace, focuses on annual scientific production, identifies the most productive authors, and highlights the most relevant sources.

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Escalating concerns over waste management and the need for sustainable energy have prompted innovative solutions at the nexus of resource recycling and self-powered applications. This study presents a novel approach to recycling super-absorbing polymer (SAP) gels from waste diapers and discarded baking sheets to fabricate a diaper waste-based triboelectric nanogenerator (DW-TENG). The DW-TENG, resembling a maraca, demonstrated superior electrical performance with a voltage output of 110 V, a current of 9 μA, and a power of 259.

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Cognitive behavioral therapy improves psychosocial outcomes in rheumatoid arthritis (RA), but access is limited. We conducted a randomized controlled trial to evaluate the efficacy of a cognitive-behavioral digital therapeutic, reclarit, on psychosocial outcomes in adult RA patients with impaired health-related quality of life. Participants were randomized to reclarit plus treatment as usual (TAU) or TAU plus educational and informational material (active control).

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Aim: To investigate the hypothesis supporting the link between periodontitis and dopaminergic neuron degeneration.

Materials And Methods: Adult male Wistar rats were used to induce dopaminergic neuronal injury with 6-hydroxydopamine (6-OHDA) neurotoxin and experimental periodontitis via ligature placement. Motor function assessments were conducted before and after periodontitis induction in controls and 6-OHDA-injury-induced rats.

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Article Synopsis
  • The study focuses on the mental health of youth affected by the Ebola epidemic in the DRC and explores anxiety and psychological distress among survivors and orphans during the COVID-19 pandemic.
  • Over half of the participants reported severe anxiety and psychological distress symptoms, with those being both survivors and orphans experiencing the highest rates.
  • Stigmatization related to Ebola and COVID-19 emerged as significant factors influencing anxiety and distress, while resilience appeared to help mitigate these mental health issues.
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We present a computational model of networked neurons developed to study the effect of temperature on neuronal synchronization in the brain in association with seizures. The network consists of a set of chaotic bursting neurons surrounding a core tonic neuron in a square lattice with periodic boundary conditions. Each neuron is reciprocally coupled to its four nearest neighbors via temperature dependent gap junctions.

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Distalization of mandibular molars comes with significant challenges, especially in adult and young adult patients. In selected cases, third molar extraction procedures offer the opportunity to place miniplates for anchorage to distalize mandibular molars, providing additional solutions to the traditional extraction of premolars or a single incisor. This approach can be of special interest to adult patients, who may have life commitments and time restraints that limit traditional orthodontic and surgical treatment options, and it can improve the efficiency of dental care.

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  • Intimate partner violence (IPV) is a significant issue in low and middle-income countries like Haiti, yet there's limited research on its links to mental health, particularly for both genders.
  • The study involved 3,586 Haitian adolescents and young adults, revealing that nearly half reported symptoms of depression and psychological distress, with IPV being a major independent predictor of these mental health issues.
  • While this research serves as an initial exploration into IPV's impact on mental health in Haiti, its cross-sectional nature means causality can't be confirmed, and it didn't account for community violence that may influence participants' mental well-being.
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Parkinson's disease is a chronic neurodegenerative disorder with no known cure characterized by motor symptoms such as tremors, rigidity, bradykinesia (slowness of movement), and postural instability. Non-motor symptoms like cognitive impairment, mood disturbances, and sleep disorders often accompany the disease. Pharmacological treatments for these symptoms are limited and frequently induce significant adverse reactions, underscoring the necessity for appropriate treatment options.

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Inflammatory myofibroblastic tumors (IMTs) represent rare neoplasms, particularly infrequent in the pediatric skull. We present a novel case of a newborn male with a 5 cm right temporal mass and discuss current diagnostic and treatment options for IMTs. A multidisciplinary effort to surgically remove the lesion was successful, and the patient's skull defect healed without neurological deficits.

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  • A nationwide survey in France asked breast cancer survivors about their thoughts on personalizing endocrine therapy (ET) to make it better for patients.
  • Most participants agreed that schedules and pill types should be customized, but many didn't have a strong opinion about how the medicine looked.
  • Many survivors wanted more information and tools, like a mobile app, to help manage side effects and understand ET's effects on their daily lives.
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  • This study looked at whether adding a procedure called lateral extra-articular tenodesis (LEAT) to knee surgery (ACL reconstruction) helps the knee heal better.
  • They tested 80 patients, splitting them into two groups: one group had just the ACL surgery and the other had ACL surgery plus LEAT.
  • After a year, the group with LEAT had less tunnel widening in their knee, but the difference in healing wasn't huge, so it didn't show a significant improvement in how well the graft healed.
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Although the high prevalence of intimate partner violence (IPV) in Haiti is well-documented, its association with post-traumatic stress disorder (PTSD) symptoms among adolescents and young adults remains unexplored. Using a representative sample of adolescents and young adults from rural and urban areas across the 10 geographical regions of Haiti, this study investigates the association between IPV and PTSD symptoms. It explores the role of social support, emotion regulation, other traumatic events, and sociodemographic factors.

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Purpose: Although data support foregoing preoperative antibiotics for outpatient, soft-tissue procedures, there is a paucity of evidence regarding antibiotics for implant-based hand procedures. The purpose of this investigation was to assess early postoperative infectious concerns for patients undergoing implant-based hand surgery, regardless of preoperative antibiotic use.

Methods: A retrospective cohort analysis was performed consisting of all patients undergoing implant-based hand procedures between January 2015 and October 2021.

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